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Gene: MID2 (midline 2) Homo sapiens
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Symbol: MID2
Name: midline 2
Description: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ37715; FLJ41813; FXY2; midin 2; midin-2; midline defect 2; midline-2; MRX101; probable E3 ubiquitin-protein ligase MID2; RING finger protein 60; RING-type E3 ubiquitin transferase MID2; RNF60; TRIM1; tripartite motif protein 1; tripartite motif-containing protein 1
Orthologs:
Mus musculus (house mouse) : Mid2 (midline 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mid2 (midline 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mid2 (midline 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MID2 (midline 2)
Canis lupus familiaris (dog) : MID2 (midline 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mid2 (midline 2)
Sus scrofa (pig) : MID2 (midline 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X107,820,453 - 107,931,637 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X107,068,889 - 107,174,867 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X106,956,116 - 107,057,077 (+)NCBINCBI36hg18NCBI36
CeleraX107,540,045 - 107,645,826 (+)NCBI
Cytogenetic MapXq22.3NCBI
HuRefX96,692,632 - 96,797,758 (+)NCBIHuRef
CHM1_1X106,979,937 - 107,085,716 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MID2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1602493
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.