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Gene: TSEN54 (tRNA splicing endonuclease subunit 54) Homo sapiens
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Symbol: TSEN54
Name: tRNA splicing endonuclease subunit 54
Description: Predicted to contribute to tRNA-intron endonuclease activity. Involved in tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to localize to the tRNA-intron endonuclease complex. Implicated in pontocerebellar hypoplasia type 2A; pontocerebellar hypoplasia type 4; and pontocerebellar hypoplasia type 5.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ37147; hsSen54; PCH2A; PCH4; PCH5; sen54; SEN54 homolog; SEN54L; tRNA-intron endonuclease Sen54; tRNA-splicing endonuclease subunit Sen54; TSEN54 tRNA splicing endonuclease subunit
Orthologs:
Mus musculus (house mouse) : Tsen54 (tRNA splicing endonuclease subunit 54)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tsen54 (tRNA splicing endonuclease subunit 54)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tsen54 (tRNA splicing endonuclease subunit 54)
Pan paniscus (bonobo/pygmy chimpanzee) : TSEN54 (tRNA splicing endonuclease subunit 54)
Canis lupus familiaris (dog) : TSEN54 (tRNA splicing endonuclease subunit 54)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tsen54 (tRNA splicing endonuclease subunit 54)
Sus scrofa (pig) : TSEN54 (tRNA splicing endonuclease subunit 54)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381775,516,528 - 75,524,735 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371773,512,609 - 73,520,821 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,024,204 - 71,032,415 (+)NCBINCBI36hg18NCBI36
Cytogenetic Map17q25.1NCBI
HuRef1768,936,266 - 68,944,477 (+)NCBIHuRef
CHM1_11773,577,646 - 73,585,857 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TSEN54
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1602635
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.