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Gene: FERMT3 (fermitin family member 3) Homo sapiens
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Symbol: FERMT3
Name: fermitin family member 3
Description: Predicted to have integrin binding activity. Involved in several processes, including integrin activation; integrin-mediated signaling pathway; and substrate adhesion-dependent cell spreading. Localizes to extracellular exosome and membrane. Implicated in leukocyte adhesion deficiency 1 and leukocyte adhesion deficiency 3. Biomarker of acute myeloid leukemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: fermitin family homolog 3; KIND3; kindlin 3; MGC10966; MIG-2; MIG2-like protein; MIG2B; UNC-112 related protein 2; unc-112-related protein 2; UNC112C; URP2; URP2SF
Orthologs:
Mus musculus (house mouse) : Fermt3 (fermitin family member 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fermt3 (fermitin family member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fermt3 (fermitin family member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : FERMT3 (fermitin family member 3)
Canis lupus familiaris (dog) : FERMT3 (fermitin family member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fermt3 (fermitin family member 3)
Sus scrofa (pig) : FERMT3 (fermitin family member 3)
Chlorocebus sabaeus (African green monkey) : FERMT3 (fermitin family member 3)
Heterocephalus glaber (naked mole-rat) : Fermt3 (fermitin family member 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1164,206,678 - 64,223,886 (+)EnsemblGRCh38hg38GRCh38
GRCh381164,206,662 - 64,223,891 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371163,974,152 - 63,991,363 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361163,730,782 - 63,747,939 (+)NCBINCBI36hg18NCBI36
Celera1161,300,902 - 61,318,205 (+)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1160,302,226 - 60,319,415 (+)NCBIHuRef
CHM1_11163,857,143 - 63,874,352 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on FERMT3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1602673
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-05-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.