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Gene: TSR2 (TSR2 ribosome maturation factor) Homo sapiens
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Symbol: TSR2
Name: TSR2 ribosome maturation factor
Description: The protein encoded by this gene appears to repress the transcription of NF-kappaB and may be involved in apoptosis. Defects in this gene are a cause of Diamond-Blackfan anemia. [provided by RefSeq, Oct 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DBA14; DT1P1A10; escortin; MGC20451; pre-rRNA-processing protein TSR2 homolog; RP1-112K5.2; TSR2, 20S rRNA accumulation, homolog; TSR2, 20S rRNA accumulation, homolog (S. cerevisiae); TSR2, ribosome maturation factor; WGG motif containing 1; WGG1
Orthologs:
Mus musculus (house mouse) : Tsr2 (TSR2 20S rRNA accumulation)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tsr2 (TSR2, ribosome maturation factor)
Chinchilla lanigera (long-tailed chinchilla) : Tsr2 (TSR2 ribosome maturation factor)
Pan paniscus (bonobo/pygmy chimpanzee) : TSR2 (TSR2 ribosome maturation factor)
Canis lupus familiaris (dog) : TSR2 (TSR2 ribosome maturation factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tsr2 (TSR2 ribosome maturation factor)
Sus scrofa (pig) : TSR2 (TSR2 ribosome maturation factor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X54,440,375 - 54,448,032 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X54,466,853 - 54,471,730 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X54,483,578 - 54,488,455 (+)NCBINCBI36hg18NCBI36
CeleraX58,299,414 - 58,304,291 (+)NCBI
Cytogenetic MapXp11.22NCBI
HuRefX51,518,075 - 51,522,307 (+)NCBIHuRef
CHM1_1X54,457,507 - 54,462,384 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TSR2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1602842
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.