Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PRDX6 (peroxiredoxin 6) Homo sapiens
Symbol: PRDX6
Name: peroxiredoxin 6
Description: Exhibits several functions, including calcium-independent phospholipase A2 activity; glutathione peroxidase activity; and protein homodimerization activity. Involved in several processes, including cellular oxidant detoxification; glycerophospholipid catabolic process; and positive regulation of mRNA splicing, via spliceosome. Localizes to the nucleus and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1-Cys; 1-Cys peroxiredoxin; 1-Cys PRX; 24 kDa protein; acidic calcium-independent phospholipase A2; aiPLA2; antioxidant protein 2; AOP2; epididymis secretory sperm binding protein Li 128m; HEL-S-128m; KIAA0106; liver 2D page spot 40; MGC46173; non-selenium glutathione peroxidase; NSGPx; p29; peroxiredoxin-6; PRX; red blood cells page spot 12
Mus musculus (house mouse) : Prdx6 (peroxiredoxin 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prdx6 (peroxiredoxin 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prdx6 (peroxiredoxin 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PRDX6 (peroxiredoxin 6)
Canis lupus familiaris (dog) : PRDX6 (peroxiredoxin 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prdx6 (peroxiredoxin 6)
Sus scrofa (pig) : PRDX6 (peroxiredoxin 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1173,477,330 - 173,488,815 (+)Ensembl
GRCh381173,477,335 - 173,488,815 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371173,446,486 - 173,457,946 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361171,713,109 - 171,724,569 (+)NCBINCBI36hg18NCBI36
Celera1146,555,898 - 146,567,358 (+)NCBI
Cytogenetic Map1q25.1NCBI
HuRef1144,671,177 - 144,682,637 (+)NCBIHuRef
CHM1_11174,868,919 - 174,880,398 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PRDX6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1602898
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.