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Gene: LAGE3 (L antigen family member 3) Homo sapiens
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Symbol: LAGE3
Name: L antigen family member 3
Description: This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CVG5; DXS9879E; DXS9951E; EKC/KEOPS complex subunit LAGE3; ESO3; GAMOS2; ITBA2; L antigen family, member 3; Pcc1; protein ESO-3
Orthologs:
Mus musculus (house mouse) : Lage3 (L antigen family, member 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lage3 (L antigen family, member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lage3 (L antigen family member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : LAGE3 (L antigen family member 3)
Canis lupus familiaris (dog) : LAGE3 (L antigen family member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lage3 (L antigen family member 3)
Sus scrofa (pig) : LAGE3 (L antigen family member 3)
more info ...
Related Pseudogenes: LAGE3P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X154,477,769 - 154,479,257 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,705,241 - 153,707,596 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,358,435 - 153,360,790 (-)NCBINCBI36hg18NCBI36
CeleraX153,866,292 - 153,868,647 (-)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,282,633 - 142,284,801 (-)NCBIHuRef
CHM1_1X153,617,753 - 153,619,241 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LAGE3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1602901
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.