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Gene: RPTOR (regulatory associated protein of MTOR complex 1) Homo sapiens
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Symbol: RPTOR
Name: regulatory associated protein of MTOR complex 1
Description: Exhibits several functions, including 14-3-3 protein binding activity; RNA polymerase III regulatory region DNA binding activity; and protein kinase regulator activity. Involved in several processes, including cellular response to leucine; positive regulation of protein phosphorylation; and positive regulation of transcription by RNA polymerase III. Localizes to several cellular components, including the TORC1 complex; cytoplasmic stress granule; and lysosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: KIAA1303; KOG1; Mip1; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; raptor; regulatory associated protein of MTOR, complex 1; regulatory-associated protein of mTOR
Orthologs:
Mus musculus (house mouse) : Rptor (regulatory associated protein of MTOR, complex 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rptor (regulatory associated protein of MTOR, complex 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rptor (regulatory associated protein of MTOR complex 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RPTOR (regulatory associated protein of MTOR complex 1)
Canis lupus familiaris (dog) : RPTOR (regulatory associated protein of MTOR complex 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rptor (regulatory associated protein of MTOR complex 1)
Sus scrofa (pig) : RPTOR (regulatory associated protein of MTOR complex 1)
Chlorocebus sabaeus (green monkey) : RPTOR (regulatory associated protein of MTOR complex 1)
Heterocephalus glaber (naked mole-rat) : Rptor (regulatory associated protein of MTOR complex 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1780,544,819 - 80,966,371 (+)Ensembl
GRCh381780,544,838 - 80,966,368 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371778,518,625 - 78,940,173 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361776,133,220 - 76,554,768 (+)NCBINCBI36hg18NCBI36
Celera1775,147,295 - 75,567,674 (+)NCBI
Cytogenetic Map17q25.3NCBI
HuRef1773,954,508 - 74,378,467 (+)NCBIHuRef
CHM1_11778,604,958 - 79,026,514 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RPTOR
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1603019
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.