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Gene: NLGN4X (neuroligin 4 X-linked) Homo sapiens
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Symbol: NLGN4X
Name: neuroligin 4 X-linked
Description: This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ASPGX2; AUTSX2; HLNX; HNL4X; HNLX; KIAA1260; MGC22376; neuroligin 4; neuroligin 4, X-linked; neuroligin X; neuroligin-4, X-linked; NLGN; NLGN4
Orthologs:
Chinchilla lanigera (long-tailed chinchilla) : Nlgn4x (neuroligin 4 X-linked)
Pan paniscus (bonobo/pygmy chimpanzee) : NLGN4X (neuroligin 4, X-linked)
Canis lupus familiaris (dog) : NLGN4X (neuroligin 4 X-linked)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nlgn4x (neuroligin 4 X-linked)
Sus scrofa (pig) : LOC100624109 (neuroligin-4, X-linked)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X5,890,026 - 6,228,882 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X5,808,067 - 6,146,916 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X5,818,083 - 6,156,706 (-)NCBINCBI36hg18NCBI36
CeleraX10,032,940 - 10,372,016 (-)NCBI
Cytogenetic MapXp22.32-p22.31NCBI
HuRefX3,686,314 - 4,028,458 (-)NCBIHuRef
CHM1_1X5,839,610 - 6,178,287 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NLGN4X
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1603020
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-07-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.