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Gene: APIP (APAF1 interacting protein) Homo sapiens
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Symbol: APIP
Name: APAF1 interacting protein
Description: Exhibits identical protein binding activity; methylthioribulose 1-phosphate dehydratase activity; and zinc ion binding activity. Involved in several processes, including L-methionine salvage from methylthioadenosine; protein homotetramerization; and pyroptosis. Localizes to the cytoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: APAF1-interacting protein; APIP2; CGI-29; CGI29; dJ179L10.2; hAPIP; methylthioribulose-1-phosphate dehydratase; MMRP19; MTRu-1-P dehydratase; probable methylthioribulose-1-phosphate dehydratase
Orthologs:
Mus musculus (house mouse) : Apip (APAF1 interacting protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Apip (APAF1 interacting protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apip (APAF1 interacting protein)
Pan paniscus (bonobo/pygmy chimpanzee) : APIP (APAF1 interacting protein)
Canis lupus familiaris (dog) : APIP (APAF1 interacting protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apip (APAF1 interacting protein)
Sus scrofa (pig) : APIP (APAF1 interacting protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1134,853,094 - 34,916,379 (-)Ensembl
GRCh381134,882,295 - 34,916,411 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371134,903,842 - 34,937,939 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361134,860,421 - 34,894,484 (-)NCBINCBI36hg18NCBI36
Celera1135,051,185 - 35,085,276 (-)NCBI
Cytogenetic Map11p13NCBI
HuRef1134,602,325 - 34,636,417 (-)NCBIHuRef
CHM1_11134,902,113 - 34,936,215 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on APIP
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1603043
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.