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Gene: TSEN2 (tRNA splicing endonuclease subunit 2) Homo sapiens
Symbol: TSEN2
Name: tRNA splicing endonuclease subunit 2
Description: Predicted to have tRNA-intron endonuclease activity. Involved in tRNA splicing, via endonucleolytic cleavage and ligation. Localizes to centrosome; cytosol; and nucleoplasm. Implicated in pontocerebellar hypoplasia type 2B.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: hsSen2; MGC2776; MGC4440; PCH2B; SEN2; SEN2L; tRNA-intron endonuclease Sen2; tRNA-splicing endonuclease subunit Sen2; TSEN2 tRNA splicing endonuclease subunit
Mus musculus (house mouse) : Tsen2 (tRNA splicing endonuclease subunit 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tsen2 (tRNA splicing endonuclease subunit 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tsen2 (tRNA splicing endonuclease subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TSEN2 (tRNA splicing endonuclease subunit 2)
Canis lupus familiaris (dog) : TSEN2 (tRNA splicing endonuclease subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tsen2 (tRNA splicing endonuclease subunit 2)
Sus scrofa (pig) : TSEN2 (tRNA splicing endonuclease subunit 2)
Chlorocebus sabaeus (African green monkey) : TSEN2 (tRNA splicing endonuclease subunit 2)
Heterocephalus glaber (naked mole-rat) : Tsen2 (tRNA splicing endonuclease subunit 2)
more info ...
Related Pseudogenes: TSEN2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl312,484,432 - 12,539,623 (+)EnsemblGRCh38hg38GRCh38
GRCh38312,484,432 - 12,539,624 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37312,517,748 - 12,580,672 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36312,501,028 - 12,549,812 (+)NCBINCBI36hg18NCBI36
Celera312,463,261 - 12,512,159 (+)NCBI
Cytogenetic Map3p25.2NCBI
HuRef312,458,994 - 12,507,895 (+)NCBIHuRef
CHM1_1312,476,015 - 12,531,209 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TSEN2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1603298
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.