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Gene: SOX5 (SRY-box transcription factor 5) Homo sapiens
Symbol: SOX5
Name: SRY-box transcription factor 5
Description: Exhibits transcription regulatory region sequence-specific DNA binding activity. Involved in asymmetric neuroblast division; cellular response to transforming growth factor beta stimulus; and positive regulation of cell differentiation. Predicted to localize to nuclear chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: L-SOX5; L-SOX5B; L-SOX5F; LAMSHF; MGC35153; RP11-444D3.1; SRY (sex determining region Y)-box 5; SRY box 5; SRY-box 5; transcription factor SOX-5
Mus musculus (house mouse) : Sox5 (SRY (sex determining region Y)-box 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sox5 (SRY-box transcription factor 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox5 (SRY-box transcription factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SOX5 (SRY-box transcription factor 5)
Canis lupus familiaris (dog) : SOX5 (SRY-box transcription factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sox5 (SRY-box transcription factor 5)
Sus scrofa (pig) : SOX5 (SRY-box transcription factor 5)
Chlorocebus sabaeus (African green monkey) : SOX5 (SRY-box transcription factor 5)
Heterocephalus glaber (naked mole-rat) : Sox5 (SRY-box transcription factor 5)
more info ...
Related Pseudogenes: SOX5P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1223,529,504 - 24,562,544 (-)EnsemblGRCh38hg38GRCh38
GRCh381223,529,499 - 24,562,701 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371223,682,438 - 24,715,383 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361223,576,498 - 24,606,647 (-)NCBINCBI36hg18NCBI36
Celera1228,833,198 - 29,862,278 (-)NCBI
Cytogenetic Map12p12.1NCBI
HuRef1223,452,599 - 24,484,456 (-)NCBIHuRef
CHM1_11223,650,324 - 24,680,623 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SOX5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1603322
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.