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Gene: DGKK (diacylglycerol kinase kappa) Homo sapiens
Symbol: DGKK
Name: diacylglycerol kinase kappa
Description: The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. [provided by RefSeq, Mar 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 142 kDa diacylglycerol kinase; DAG kinase kappa; DGK-kappa; diacylglycerol kinase, kappa; diglyceride kinase kappa; MRX68
Mus musculus (house mouse) : Dgkk (diacylglycerol kinase kappa)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dgkk (diacylglycerol kinase kappa)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dgkk (diacylglycerol kinase kappa)
Pan paniscus (bonobo/pygmy chimpanzee) : DGKK (diacylglycerol kinase kappa)
Canis lupus familiaris (dog) : DGKK (diacylglycerol kinase kappa)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dgkk (diacylglycerol kinase kappa)
Sus scrofa (pig) : DGKK (diacylglycerol kinase kappa)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X50,365,407 - 50,470,851 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X50,111,879 - 50,213,721 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X50,128,637 - 50,230,477 (-)NCBINCBI36hg18NCBI36
CeleraX54,155,478 - 54,257,318 (-)NCBI
Cytogenetic MapXp11.22NCBI
HuRefX47,555,690 - 47,658,066 (-)NCBIHuRef
CHM1_1X50,188,236 - 50,293,462 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DGKK
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1603361
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.