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Gene: TMEM106B (transmembrane protein 106B) Homo sapiens
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Symbol: TMEM106B
Name: transmembrane protein 106B
Description: Involved in dendrite morphogenesis and lysosome localization. Localizes to the endosome and lysosomal membrane. Implicated in hypomyelinating leukodystrophy; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methylcholine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ11273; HLD16; MGC33727
Orthologs:
Mus musculus (house mouse) : Tmem106b (transmembrane protein 106B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tmem106b (transmembrane protein 106B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmem106b (transmembrane protein 106B)
Pan paniscus (bonobo/pygmy chimpanzee) : TMEM106B (transmembrane protein 106B)
Canis lupus familiaris (dog) : TMEM106B (transmembrane protein 106B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmem106b (transmembrane protein 106B)
Sus scrofa (pig) : TMEM106B (transmembrane protein 106B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38712,211,294 - 12,243,367 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37712,250,848 - 12,276,890 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36712,217,451 - 12,243,411 (+)NCBINCBI36hg18NCBI36
Celera712,228,868 - 12,254,926 (+)NCBI
Cytogenetic Map7p21.3NCBI
HuRef712,126,997 - 12,153,058 (+)NCBIHuRef
CHM1_1712,251,533 - 12,277,588 (+)NCBICHM1_1
CRA_TCAGchr7v2712,304,117 - 12,330,178 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on TMEM106B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1603394
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.