Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: CR1 (complement C3b/C4b receptor 1 (Knops blood group)) Homo sapiens
Analyze
Symbol: CR1
Name: complement C3b/C4b receptor 1 (Knops blood group)
Description: Exhibits complement receptor activity and opsonin binding activity. Involved in negative regulation of complement activation and regulation of serine-type endopeptidase activity. Localizes to the cell surface and integral component of plasma membrane. Implicated in malaria.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C3-binding protein; C3b/C4b receptor; C3BR; C4BR; CD35; CD35 antigen; complement component (3b/4b) receptor 1 (Knops blood group); complement component 3b/4b receptor 1 (Knops blood group); complement component receptor 1; complement receptor 1; complement receptor type 1; KN; Knops blood group antigen
Orthologs:
Pan paniscus (bonobo/pygmy chimpanzee) : CR1 (complement C3b/C4b receptor 1 (Knops blood group))
Canis lupus familiaris (dog) : CR1L (complement C3b/C4b receptor 1 like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cr1 (complement C3b/C4b receptor 1 (Knops blood group))
Sus scrofa (pig) : CR1 (complement C3b/C4b receptor 1 (Knops blood group))
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381207,496,152 - 207,641,765 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371207,669,473 - 207,815,110 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361205,736,096 - 205,881,733 (+)NCBINCBI36hg18NCBI36
Celera1180,918,501 - 181,045,588 (+)NCBI
Cytogenetic Map1q32.2NCBI
HuRef1178,362,547 - 178,489,425 (+)NCBIHuRef
CHM1_11208,942,210 - 209,087,469 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CR1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1603411
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.