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Gene: SLX1A (SLX1 homolog A, structure-specific endonuclease subunit) Homo sapiens
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Symbol: SLX1A
Name: SLX1 homolog A, structure-specific endonuclease subunit
Description: Exhibits 5'-flap endonuclease activity and crossover junction endodeoxyribonuclease activity. Involved in DNA metabolic process and negative regulation of telomere maintenance via telomere lengthening. Localizes to the Slx1-Slx4 complex and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GIY-YIG domain containing 1; GIY-YIG domain-containing protein 1; GIYD1; GIYD2; SLX1 structure-specific endonuclease subunit homolog A; SLX1B; structure-specific endonuclease subunit SLX1
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1630,193,887 - 30,197,561 (+)Ensembl
GRCh381630,193,843 - 30,197,566 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371630,205,164 - 30,208,887 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,112,718 - 30,116,383 (+)NCBINCBI36hg18NCBI36
Cytogenetic Map16p11.2NCBI
HuRef1627,867,802 - 27,871,526 (+)NCBIHuRef
CHM1_11631,419,788 - 31,423,513 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SLX1A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1603444
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.