Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: MESP1 (mesoderm posterior bHLH transcription factor 1) Homo sapiens
Symbol: MESP1
Name: mesoderm posterior bHLH transcription factor 1
CRRD ID: 1603631
Description: Exhibits DNA-binding transcription factor activity and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including endothelial cell differentiation; heart development; and positive regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin; INTERACTS WITH 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bHLHc5; class C basic helix-loop-helix protein 5; mesoderm posterior 1 homolog; mesoderm posterior basic helix-loop-helix transcription factor 1; mesoderm posterior protein 1; MGC10676
Mus musculus (house mouse) : Mesp1 (mesoderm posterior 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mesp1 (mesoderm posterior bHLH transcription factor 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MESP1 (mesoderm posterior bHLH transcription factor 1)
Canis lupus familiaris (dog) : MESP1 (mesoderm posterior bHLH transcription factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mesp1 (mesoderm posterior bHLH transcription factor 1)
Sus scrofa (pig) : MESP1 (mesoderm posterior bHLH transcription factor 1)
Chlorocebus sabaeus (African green monkey) : MESP1 (mesoderm posterior bHLH transcription factor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1589,748,661 - 89,751,310 (-)EnsemblGRCh38hg38GRCh38
GRCh381589,734,772 - 89,751,309 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371590,293,098 - 90,294,540 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361588,094,110 - 88,095,552 (-)NCBINCBI36hg18NCBI36
Celera1566,695,858 - 66,697,300 (-)NCBI
Cytogenetic Map15q26.1NCBI
HuRef1566,406,054 - 66,407,496 (-)NCBIHuRef
CHM1_11590,133,926 - 90,135,368 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MESP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1603631
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.