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Gene: SRGAP2 (SLIT-ROBO Rho GTPase activating protein 2) Homo sapiens
Symbol: SRGAP2
Name: SLIT-ROBO Rho GTPase activating protein 2
Description: Exhibits GTPase activator activity; Rac GTPase binding activity; and protein homodimerization activity. Involved in several processes, including generation of neurons; plasma membrane bounded cell projection assembly; and substrate adhesion-dependent cell spreading. Localizes to several cellular components, including the dendritic spine head; lamellipodium; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ARHGAP34; FNBP2; formin binding protein 2; formin-binding protein 2; KIAA0456; rho GTPase-activating protein 34; RP11-312O7.2; SLIT-ROBO GAP2; SLIT-ROBO Rho GTPase-activating protein 2; SRGAP2A; srGAP3
Mus musculus (house mouse) : Srgap2 (SLIT-ROBO Rho GTPase activating protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Srgap2 (SLIT-ROBO Rho GTPase activating protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srgap2 (SLIT-ROBO Rho GTPase activating protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SRGAP2 (SLIT-ROBO Rho GTPase activating protein 2)
Canis lupus familiaris (dog) : SRGAP2 (SLIT-ROBO Rho GTPase activating protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srgap2 (SLIT-ROBO Rho GTPase activating protein 2)
Sus scrofa (pig) : SRGAP2 (SLIT-ROBO Rho GTPase activating protein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381206,203,556 - 206,464,443 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371206,135,293 - 206,135,657 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh371206,516,197 - 206,637,783 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361204,582,823 - 204,704,406 (+)NCBINCBI36hg18NCBI36
Celera1179,840,685 - 179,889,229 (+)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1177,269,281 - 177,336,031 (+)NCBIHuRef
CHM1_11207,650,968 - 207,909,982 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SRGAP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1603684
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.