Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: MIR511 (microRNA 511) Homo sapiens
Analyze
Symbol: MIR511
Name: microRNA 511
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: hsa-mir-511; hsa-mir-511-2; mir-511; MIR511-1; MIR511-2; MIRN511-1; MIRN511-2
Orthologs:
Mus musculus (house mouse) : Mir511 (microRNA 511)  MGI
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381017,845,107 - 17,845,193 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371017,887,107 - 17,887,193 (+)NCBIGRCh37GRCh37hg19GRCh37
Celera1017,820,543 - 17,820,629 (+)NCBI
Cytogenetic Map10p12.33NCBI
HuRef1017,800,111 - 17,800,197 (+)NCBIHuRef
CHM1_11017,887,059 - 17,887,145 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Sequence

Nucleotide Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MIR511
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1603777
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.