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Gene: HVCN1 (hydrogen voltage gated channel 1) Homo sapiens
Symbol: HVCN1
Name: hydrogen voltage gated channel 1
Description: Exhibits identical protein binding activity and voltage-gated proton channel activity. Involved in cellular response to pH; cellular response to zinc ion; and proton transmembrane transport. Localizes to the integral component of plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HV1; hydrogen voltage-gated channel 1; MGC15619; voltage sensor domain-only protein; voltage-gated hydrogen channel 1; VSOP
Mus musculus (house mouse) : Hvcn1 (hydrogen voltage-gated channel 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hvcn1 (hydrogen voltage-gated channel 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hvcn1 (hydrogen voltage gated channel 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HVCN1 (hydrogen voltage gated channel 1)
Canis lupus familiaris (dog) : HVCN1 (hydrogen voltage gated channel 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hvcn1 (hydrogen voltage gated channel 1)
Sus scrofa (pig) : HVCN1 (hydrogen voltage gated channel 1)
Chlorocebus sabaeus (African green monkey) : HVCN1 (hydrogen voltage gated channel 1)
Heterocephalus glaber (naked mole-rat) : Hvcn1 (hydrogen voltage gated channel 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl12110,627,841 - 110,704,950 (-)EnsemblGRCh38hg38GRCh38
GRCh3812110,648,686 - 110,704,945 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712111,086,491 - 111,130,276 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612109,570,874 - 109,612,000 (-)NCBINCBI36hg18NCBI36
Celera12110,713,319 - 110,754,445 (-)NCBI
Cytogenetic Map12q24.11NCBI
HuRef12108,104,197 - 108,145,322 (-)NCBIHuRef
CHM1_112111,054,153 - 111,095,269 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on HVCN1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1603943
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.