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Gene: REG3A (regenerating family member 3 alpha) Homo sapiens
Symbol: REG3A
Name: regenerating family member 3 alpha
CRRD ID: 1604065
Description: Exhibits identical protein binding activity. Predicted to be involved in several processes, including defense response to bacterium; negative regulation of keratinocyte differentiation; and positive regulation of keratinocyte proliferation. Predicted to localize to extracellular space. Biomarker of hepatocellular carcinoma and liver cirrhosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ18565; hepatocarcinoma-intestine-pancreas; hepatointestinal pancreatic protein; HIP; HIP/PAP; human proislet peptide; INGAP; pancreatic beta cell growth factor; pancreatitis-associated protein 1; PAP; PAP homologous protein; PAP-H; PAP1; PBCGF; proliferation-inducing protein 34; proliferation-inducing protein 42; reg III-alpha; REG-3-alpha; REG-III; REG3; regenerating islet-derived 3 alpha; regenerating islet-derived protein 3-alpha; regenerating islet-derived protein III-alpha
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl279,157,003 - 79,159,753 (-)EnsemblGRCh38hg38GRCh38
GRCh38279,157,006 - 79,159,753 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37279,384,132 - 79,386,880 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36279,237,641 - 79,240,387 (-)NCBINCBI36hg18NCBI36
Celera279,212,862 - 79,215,608 (-)NCBI
Cytogenetic Map2p12NCBI
HuRef279,119,456 - 79,122,204 (-)NCBIHuRef
CHM1_1279,313,660 - 79,316,408 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on REG3A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604065
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-09-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.