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Gene: TOR1AIP2 (torsin 1A interacting protein 2) Homo sapiens
Symbol: TOR1AIP2
Name: torsin 1A interacting protein 2
Description: One of the two protein isoforms encoded by this gene is a type II integral membrane protein found in the endoplasmic reticulum (ER). The encoded protein is a cofactor for the ATPase TorsinA, regulating the amount of TorsinA present in the ER compared to that found in the nuclear envelope. Defects in this protein are a cause of early onset primary dystonia, a neuromuscular disease. The other isoform encoded by this gene is an interferon alpha responsive protein whose cellular role has yet to be determined. [provided by RefSeq, Mar 2017]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ77012; IFRG15; interferon alpha responsive protein; interferon responsive gene 15; LULL1; lumenal domain like LAP1; lumenal domain-like LAP1; MGC120074; MGC120075; MGC120076; MGC120077; MGC126581; MGC138430; NET9; RP11-12M5.5; torsin A interacting protein 2; torsin-1A-interacting protein 2
Mus musculus (house mouse) : Tor1aip2 (torsin A interacting protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tor1aip2 (torsin 1A interacting protein 2)  Alliance
Canis lupus familiaris (dog) : LOC106557472 (torsin-1A-interacting protein 2-like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC106144612 (torsin-1A-interacting protein 2)
Sus scrofa (pig) : TOR1AIP2 (torsin 1A interacting protein 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381179,839,976 - 179,877,803 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371179,809,102 - 179,847,867 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361178,080,576 - 178,113,557 (-)NCBINCBI36hg18NCBI36
Celera1152,920,678 - 152,954,553 (-)NCBI
Cytogenetic Map1q25.2NCBI
HuRef1151,040,947 - 151,078,786 (-)NCBIHuRef
CHM1_11181,232,909 - 181,270,748 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TOR1AIP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604221
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.