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Gene: TCHP (trichoplein keratin filament binding) Homo sapiens
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Symbol: TCHP
Name: trichoplein keratin filament binding
Description: Involved in apoptotic process; negative regulation of cell growth; and negative regulation of cilium assembly. Localizes to several cellular components, including apical cortex; cytoskeleton; and mitochondrion; INTERACTS WITH 2-hydroxypropanoic acid; atrazine; copper(II) sulfate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC10854; mitochondrial protein with oncostatic activity; mitostatin; TpMs; trichoplein keratin filament-binding protein; trichoplein, keratin filament binding; tumor suppressor protein
Orthologs:
Mus musculus (house mouse) : Tchp (trichoplein, keratin filament binding)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tchp (trichoplein, keratin filament binding)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tchp (trichoplein keratin filament binding)
Pan paniscus (bonobo/pygmy chimpanzee) : TCHP (trichoplein keratin filament binding)
Canis lupus familiaris (dog) : TCHP (trichoplein keratin filament binding)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tchp (trichoplein keratin filament binding)
Sus scrofa (pig) : TCHP (trichoplein keratin filament binding)
Chlorocebus sabaeus (African green monkey) : TCHP (trichoplein keratin filament binding)
Heterocephalus glaber (naked mole-rat) : Tchp (trichoplein keratin filament binding)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl12109,900,264 - 109,983,841 (+)EnsemblGRCh38hg38GRCh38
GRCh3812109,880,667 - 109,918,069 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712110,338,079 - 110,355,874 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612108,822,706 - 108,840,251 (+)NCBINCBI36hg18NCBI36
Celera12109,962,427 - 109,980,222 (+)NCBI
Cytogenetic Map12q24.11NCBI
HuRef12107,354,164 - 107,371,959 (+)NCBIHuRef
CHM1_112110,305,866 - 110,323,661 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TCHP
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604269
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.