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Gene: TRAF7 (TNF receptor associated factor 7) Homo sapiens
Symbol: TRAF7
Name: TNF receptor associated factor 7
Description: Exhibits ubiquitin-protein transferase activity. Involved in several processes, including positive regulation of apoptotic signaling pathway; protein ubiquitination; and regulation of MAPK cascade. Localizes to the intracellular membrane-bounded organelle; plasma membrane; and ubiquitin ligase complex.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CAFDADD; DKFZp586I021; E3 ubiquitin-protein ligase TRAF7; MGC7807; RFWD1; ring finger and WD repeat domain 1; RING finger and WD repeat-containing protein 1; RING finger protein 119; RING-type E3 ubiquitin transferase TRAF7; RNF119; TNF receptor-associated factor 7; TNF receptor-associated factor 7, E3 ubiquitin protein ligase
Mus musculus (house mouse) : Traf7 (TNF receptor-associated factor 7)  MGI  Alliance
Rattus norvegicus (Norway rat) : Traf7 (TNF receptor associated factor 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Traf7 (TNF receptor associated factor 7)
Pan paniscus (bonobo/pygmy chimpanzee) : TRAF7 (TNF receptor associated factor 7)
Canis lupus familiaris (dog) : TRAF7 (TNF receptor associated factor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Traf7 (TNF receptor associated factor 7)
Sus scrofa (pig) : TRAF7 (TNF receptor associated factor 7)
Chlorocebus sabaeus (African green monkey) : TRAF7 (TNF receptor associated factor 7)
Heterocephalus glaber (naked mole-rat) : Traf7 (TNF receptor associated factor 7)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl162,155,698 - 2,178,129 (+)Ensembl
GRCh38162,155,778 - 2,178,129 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37162,205,763 - 2,228,130 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,145,800 - 2,168,131 (+)NCBINCBI36hg18NCBI36
Celera162,420,218 - 2,442,550 (+)NCBI
Cytogenetic Map16p13.3NCBI
HuRef162,132,066 - 2,154,384 (+)NCBIHuRef
CHM1_1162,205,774 - 2,228,103 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TRAF7
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604273
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-12-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.