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Gene: CDT1 (chromatin licensing and DNA replication factor 1) Homo sapiens
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Symbol: CDT1
Name: chromatin licensing and DNA replication factor 1
Description: Exhibits chromatin binding activity. Involved in several processes, including negative regulation of cell cycle; regulation of DNA-dependent DNA replication; and regulation of protein localization to kinetochore. Localizes to the kinetochore and nuclear body. Implicated in Meier-Gorlin syndrome 4.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DNA replication factor Cdt1; double parked homolog; Double parked, Drosophila, homolog of; DUP; RIS2
Orthologs:
Mus musculus (house mouse) : Cdt1 (chromatin licensing and DNA replication factor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdt1 (chromatin licensing and DNA replication factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdt1 (chromatin licensing and DNA replication factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CDT1 (chromatin licensing and DNA replication factor 1)
Canis lupus familiaris (dog) : CDT1 (chromatin licensing and DNA replication factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdt1 (chromatin licensing and DNA replication factor 1)
Sus scrofa (pig) : CDT1 (chromatin licensing and DNA replication factor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381688,803,789 - 88,809,258 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371688,870,186 - 88,875,666 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,397,687 - 87,403,167 (+)NCBINCBI36hg18NCBI36
Celera1673,938,823 - 73,944,303 (+)NCBI
Cytogenetic Map16q24.3NCBI
HuRef1674,567,412 - 74,572,892 (+)NCBIHuRef
CHM1_11690,281,453 - 90,286,933 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on CDT1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604278
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.