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Gene: LBH (LBH regulator of WNT signaling pathway) Homo sapiens
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Symbol: LBH
Name: LBH regulator of WNT signaling pathway
Description: Involved in negative regulation of transcription, DNA-templated; positive regulation of transcription, DNA-templated; and regulation of MAPK cascade. Localizes to the cytoplasm; nucleus; and protein-containing complex; INTERACTS WITH (-)-demecolcine; 17beta-estradiol; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp566J091; hLBH; limb bud and heart development; limb bud and heart development homolog; limb bud and heart development protein homolog; MGC104312; MGC163287
Orthologs:
Mus musculus (house mouse) : Lbh (limb-bud and heart)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lbh (LBH regulator of WNT signaling pathway)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lbh (LBH regulator of WNT signaling pathway)
Pan paniscus (bonobo/pygmy chimpanzee) : LBH (LBH regulator of WNT signaling pathway)
Canis lupus familiaris (dog) : LBH (LBH regulator of WNT signaling pathway)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lbh (LBH regulator of WNT signaling pathway)
Sus scrofa (pig) : LBH (LBH regulator of WNT signaling pathway)
Chlorocebus sabaeus (African green monkey) : LBH (LBH regulator of WNT signaling pathway)
Heterocephalus glaber (naked mole-rat) : Lbh (LBH regulator of WNT signaling pathway)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl230,231,534 - 30,323,730 (+)Ensembl
GRCh38230,231,534 - 30,260,028 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37230,454,397 - 30,482,899 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36230,307,901 - 30,336,403 (+)NCBINCBI36hg18NCBI36
Celera230,288,761 - 30,325,820 (+)NCBI
Cytogenetic Map2p23.1NCBI
HuRef230,192,937 - 30,221,438 (+)NCBIHuRef
CHM1_1230,384,624 - 30,413,128 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LBH
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604281
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.