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Gene: PVRIG (PVR related immunoglobulin domain containing) Homo sapiens
Symbol: PVRIG
Name: PVR related immunoglobulin domain containing
Description: Exhibits phosphatase binding activity and signaling receptor activity. Involved in negative regulation of T cell receptor signaling pathway. Localizes to the plasma membrane; INTERACTS WITH (-)-demecolcine; 2-hydroxypropanoic acid; antirheumatic drug.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C7orf15; CD112 receptor; CD112R; MGC104322; MGC138295; MGC138297; MGC2463; nectin-2 receptor; poliovirus receptor related immunoglobulin domain containing; poliovirus receptor-related immunoglobulin domain-containing protein; transmembrane protein PVRIG
Mus musculus (house mouse) : Pvrig (poliovirus receptor related immunoglobulin domain containing)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pvrig (PVR related immunoglobulin domain containing)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pvrig (PVR related immunoglobulin domain containing)
Pan paniscus (bonobo/pygmy chimpanzee) : PVRIG (PVR related immunoglobulin domain containing)
Canis lupus familiaris (dog) : PVRIG (PVR related immunoglobulin domain containing)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pvrig (PVR related immunoglobulin domain containing)
Sus scrofa (pig) : PVRIG (PVR related immunoglobulin domain containing)
Chlorocebus sabaeus (African green monkey) : PVRIG (PVR related immunoglobulin domain containing)
more info ...
Related Pseudogenes: PVRIG2P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl7100,218,241 - 100,221,490 (+)Ensembl
GRCh387100,218,625 - 100,221,489 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37799,816,147 - 99,819,113 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36799,654,807 - 99,657,047 (+)NCBINCBI36hg18NCBI36
Celera794,552,220 - 94,554,458 (+)NCBI
Cytogenetic Map7q22.1NCBI
HuRef794,451,626 - 94,453,866 (+)NCBIHuRef
CHM1_1799,746,940 - 99,749,176 (+)NCBICHM1_1
CRA_TCAGchr7v2799,176,957 - 99,179,197 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PVRIG
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604301
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.