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Gene: STK26 (serine/threonine kinase 26) Homo sapiens
Symbol: STK26
Name: serine/threonine kinase 26
Description: The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: mammalian Ste20-like protein kinase 4; mammalian sterile 20-like 4; MASK; MST-4; Mst3 and SOK1-related kinase; MST4; serine/threonine protein kinase 26; serine/threonine protein kinase MASK; serine/threonine protein kinase MST4; serine/threonine-protein kinase 26; serine/threonine-protein kinase MASK; serine/threonine-protein kinase MST4; STE20-like kinase 4; STE20-like kinase MST4
Mus musculus (house mouse) : Stk26 (serine/threonine kinase 26)  MGI  Alliance
Rattus norvegicus (Norway rat) : Stk26 (serine/threonine kinase 26)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stk26 (serine/threonine kinase 26)
Pan paniscus (bonobo/pygmy chimpanzee) : STK26 (serine/threonine kinase 26)
Canis lupus familiaris (dog) : STK26 (serine/threonine kinase 26)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stk26 (serine/threonine kinase 26)
Sus scrofa (pig) : STK26 (serine/threonine kinase 26)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X132,023,217 - 132,075,943 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X131,157,245 - 131,209,971 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X130,984,926 - 131,037,652 (+)NCBINCBI36hg18NCBI36
CeleraX131,543,656 - 131,596,380 (+)NCBI
Cytogenetic MapXq26.2NCBI
HuRefX120,561,932 - 120,614,415 (+)NCBIHuRef
CHM1_1X131,068,821 - 131,121,548 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on STK26
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604356
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.