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Gene: DSTYK (dual serine/threonine and tyrosine protein kinase) Homo sapiens
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Symbol: DSTYK
Name: dual serine/threonine and tyrosine protein kinase
Description: Predicted to have ATP binding activity and protein kinase activity. Involved in several processes, including cellular response to fibroblast growth factor stimulus; positive regulation of fibroblast growth factor receptor signaling pathway; and positive regulation of phosphorylation. Localizes to apical plasma membrane; basolateral plasma membrane; and cytoplasm. Implicated in CAKUT1 and hereditary spastic paraplegia 23.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CAKUT1; dusty PK; dusty protein kinase; DustyPK; HDCMD38P; KIAA0472; receptor interacting protein 5; receptor interacting protein kinase 5; receptor-interacting serine/threonine-protein kinase 5; RIP-homologous kinase; RIP5; RIPK5; sgK496; spastic paraplegia 23 (autosomal recessive); SPG23; sugen kinase 496
Orthologs:
Mus musculus (house mouse) : Dstyk (dual serine/threonine and tyrosine protein kinase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dstyk (dual serine/threonine and tyrosine protein kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dstyk (dual serine/threonine and tyrosine protein kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : DSTYK (dual serine/threonine and tyrosine protein kinase)
Canis lupus familiaris (dog) : DSTYK (dual serine/threonine and tyrosine protein kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dstyk (dual serine/threonine and tyrosine protein kinase)
Sus scrofa (pig) : DSTYK (dual serine/threonine and tyrosine protein kinase)
Chlorocebus sabaeus (African green monkey) : DSTYK (dual serine/threonine and tyrosine protein kinase)
Heterocephalus glaber (naked mole-rat) : Dstyk (dual serine/threonine and tyrosine protein kinase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1205,142,505 - 205,211,702 (-)EnsemblGRCh38hg38GRCh38
GRCh381205,142,497 - 205,211,702 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371205,111,631 - 205,180,727 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361203,378,256 - 203,447,313 (-)NCBINCBI36hg18NCBI36
Celera1178,246,858 - 178,315,803 (-)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1176,276,947 - 176,346,439 (-)NCBIHuRef
CHM1_11206,534,987 - 206,604,027 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Nomenclature History
 
More on DSTYK
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604373
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.