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Gene: FOXM1 (forkhead box M1) Homo sapiens
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Symbol: FOXM1
Name: forkhead box M1
Description: Exhibits DNA-binding transcription factor activity; RNA polymerase II regulatory region sequence-specific DNA binding activity; and protein kinase binding activity. Involved in several processes, including DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; regulation of intracellular signal transduction; and regulation of nucleobase-containing compound metabolic process. Predicted to localize to the nuclear chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: a novel forkhead box M1 isoform FOXM1D; FKHL16; forkhead box M1-D; forkhead box protein M1; Forkhead, drosophila, homolog-like 16; forkhead-like 16; forkhead-related protein FKHL16; FOXM1A; FOXM1B; FOXM1C; hepatocyte nuclear factor 3 forkhead homolog 11; HFH-11; HFH11; HNF-3; HNF-3/fork-head homolog 11; INS-1; M-phase phosphoprotein 2; MPHOSPH2; MPM-2 reactive phosphoprotein 2; MPP-2; MPP2; PIG29; TGT3; transcription factor Trident; TRIDENT; winged-helix factor from INS-1 cells
Orthologs:
Mus musculus (house mouse) : Foxm1 (forkhead box M1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Foxm1 (forkhead box M1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxm1 (forkhead box M1)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXM1 (forkhead box M1)
Canis lupus familiaris (dog) : FOXM1 (forkhead box M1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxm1 (forkhead box M1)
Sus scrofa (pig) : FOXM1 (forkhead box M1)
Chlorocebus sabaeus (green monkey) : FOXM1 (forkhead box M1)
Heterocephalus glaber (naked mole-rat) : Foxm1 (forkhead box M1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl122,857,681 - 2,877,155 (-)Ensembl
GRCh38122,857,680 - 2,877,174 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37122,966,846 - 2,986,321 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,837,110 - 2,856,564 (-)NCBINCBI36hg18NCBI36
Celera124,580,805 - 4,600,257 (-)NCBI
Cytogenetic Map12p13.33NCBI
HuRef122,824,362 - 2,843,552 (-)NCBIHuRef
CHM1_1122,966,095 - 2,985,580 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on FOXM1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604404
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.