Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ALKAL1 (ALK and LTK ligand 1) Homo sapiens
Symbol: ALKAL1
Name: ALK and LTK ligand 1
Description: Exhibits receptor signaling protein tyrosine kinase activator activity and receptor tyrosine kinase binding activity. Involved in positive regulation of ERK1 and ERK2 cascade; positive regulation of ERK5 cascade; and positive regulation of neuron projection development. Predicted to localize to extracellular region; INTERACTS WITH amiodarone; fonofos; paracetamol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AUG-beta; AUGA; AUGB; augmentor beta; augmentor-alpha; FAM150A; family with sequence similarity 150 member A; family with sequence similarity 150, member A; hypothetical protein LOC389658; MGC163513; MGC163515; RPLK9433; UNQ9433
Mus musculus (house mouse) : Alkal1 (ALK and LTK ligand 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Alkal1 (ALK and LTK ligand 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ALKAL1 (ALK and LTK ligand 1)
Canis lupus familiaris (dog) : ALKAL1 (ALK and LTK ligand 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alkal1 (ALK and LTK ligand 1)
Sus scrofa (pig) : ALKAL1 (ALK and LTK ligand 1)
Chlorocebus sabaeus (African green monkey) : ALKAL1 (ALK and LTK ligand 1)
Heterocephalus glaber (naked mole-rat) : Alkal1 (ALK and LTK ligand 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl852,534,037 - 52,565,430 (-)EnsemblGRCh38hg38GRCh38
GRCh38852,534,037 - 52,565,430 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37853,446,597 - 53,478,021 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36853,609,251 - 53,640,574 (-)NCBINCBI36hg18NCBI36
Celera849,436,928 - 49,468,353 (-)NCBI
Cytogenetic Map8q11.23NCBI
HuRef848,914,390 - 48,945,583 (-)NCBIHuRef
CHM1_1853,498,972 - 53,530,389 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ALKAL1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604440
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.