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Gene: PPP2R3B (protein phosphatase 2 regulatory subunit B''beta) Homo sapiens
Symbol: PPP2R3B
Name: protein phosphatase 2 regulatory subunit B''beta
Description: Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. [provided by RefSeq, Apr 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ60425; NY-REN-8; NY-REN-8 antigen; NYREN8; PP2A, subunit B, PR48 isoform; PPP2R3L; PPP2R3LY; PR48; PR70; protein phosphatase 2 (formerly 2A), regulatory subunit B'', beta; serine/threonine protein phosphatase 2A, 48kDa regulatory subunit B; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X333,933 - 387,327 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38Y333,933 - 387,327 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37Y244,668 - 297,690 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37X294,668 - 347,690 (-)ENTREZGENEGRCh37GRCh37hg19GRCh37
Build 36X214,970 - 267,627 (-)NCBINCBI36hg18NCBI36
Build 36Y214,970 - 267,627 (-)NCBINCBI36hg18NCBI36
CeleraX734,571 - 788,070 (+)NCBI
Cytogenetic MapXp22.33 and Yp11.31NCBI
CHM1_1X278,231 - 331,243 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PPP2R3B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604626
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.