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Gene: PHLPP2 (PH domain and leucine rich repeat protein phosphatase 2) Homo sapiens
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Symbol: PHLPP2
Name: PH domain and leucine rich repeat protein phosphatase 2
Description: Predicted to have metal ion binding activity and protein serine/threonine phosphatase activity. Predicted to be involved in negative regulation of protein kinase B signaling. Localizes to the cytoplasm; PARTICIPATES IN phosphatidylinositol 3-kinase-Akt signaling pathway; protein kinase C (PKC) signaling pathway; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; acetaldehyde; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KIAA0931; PH domain and leucine rich repeat protein phosphatase-like; PH domain leucine-rich repeat-containing protein phosphatase 2; PH domain leucine-rich repeat-containing protein phosphatase-like; PHLPP-like; PHLPPL; PPM3B
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381671,644,924 - 71,724,701 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371671,678,827 - 71,757,798 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361670,236,353 - 70,306,205 (-)NCBINCBI36hg18NCBI36
Celera1655,994,913 - 56,064,759 (-)NCBI
Cytogenetic Map16q22.2NCBI
HuRef1657,446,695 - 57,516,253 (-)NCBIHuRef
CHM1_11673,091,589 - 73,171,419 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PHLPP2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604636
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.