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Gene: ZACN (zinc activated ion channel) Homo sapiens
Symbol: ZACN
Name: zinc activated ion channel
Description: Exhibits ligand-gated ion channel activity. Predicted to contribute to extracellular ligand-gated ion channel activity. Involved in ion transmembrane transport and response to zinc ion. Localizes to the plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: L2; LGICZ; LGICZ1; ligand-gated ion channel subunit; ligand-gated ion channel zinc-activated 1; ligand-gated ion channel, zinc activated 1; ligand-gated ion-channel receptor L2; MGC129841; ZAC; ZAC1; zinc activated ligand-gated ion channel 1; zinc-activated ligand-gated ion channel
Mus musculus (house mouse) : Pcdhb12 (protocadherin beta 12)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zacn (zinc activated ion channel)
Pan paniscus (bonobo/pygmy chimpanzee) : ZACN (zinc activated ion channel)
Canis lupus familiaris (dog) : ZACN (zinc activated ion channel)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zacn (zinc activated ion channel)
Sus scrofa (pig) : ZACN (zinc activated ion channel)
Chlorocebus sabaeus (African green monkey) : ZACN (zinc activated ion channel)
Heterocephalus glaber (naked mole-rat) : Zacn (zinc activated ion channel)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1776,071,961 - 76,083,666 (+)Ensembl
GRCh381776,079,182 - 76,082,806 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371774,075,263 - 74,078,885 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361771,586,904 - 71,590,342 (+)NCBINCBI36hg18NCBI36
Celera1770,669,095 - 70,672,716 (+)NCBI
Cytogenetic Map17q25.1NCBI
HuRef1769,504,190 - 69,507,812 (+)NCBIHuRef
CHM1_11774,140,204 - 74,143,826 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ZACN
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604695
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.