Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: GSAP (gamma-secretase activating protein) Homo sapiens
Analyze
Symbol: GSAP
Name: gamma-secretase activating protein
Description: Exhibits amyloid-beta binding activity. Involved in positive regulation of amyloid-beta formation and regulation of proteolysis. Localizes to the trans-Golgi network.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp667B242; gamma-secretase-activating protein; MGC126548; pigeon homolog; PION
Orthologs:
Mus musculus (house mouse) : Gsap (gamma-secretase activating protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gsap (gamma-secretase activating protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gsap (gamma-secretase activating protein)
Pan paniscus (bonobo/pygmy chimpanzee) : GSAP (gamma-secretase activating protein)
Canis lupus familiaris (dog) : GSAP (gamma-secretase activating protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gsap (gamma-secretase activating protein)
Sus scrofa (pig) : GSAP (gamma-secretase activating protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38777,310,751 - 77,416,419 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37776,940,068 - 77,045,719 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36776,778,004 - 76,883,653 (-)NCBINCBI36hg18NCBI36
Celera771,640,697 - 71,746,347 (-)NCBI
Cytogenetic Map7q11.23NCBI
HuRef771,542,397 - 71,647,114 (-)NCBIHuRef
CHM1_1776,870,032 - 76,975,785 (-)NCBICHM1_1
CRA_TCAGchr7v2776,273,131 - 76,378,780 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on GSAP
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604809
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.