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Gene: LIMCH1 (LIM and calponin homology domains 1) Homo sapiens
Symbol: LIMCH1
Name: LIM and calponin homology domains 1
Description: Exhibits myosin II head/neck binding activity. Involved in several processes, including cytoplasmic actin-based contraction involved in cell motility; positive regulation of stress fiber assembly; and regulation of focal adhesion assembly. Localizes to stress fiber. Colocalizes with myosin II complex; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp434I0312; DKFZp686A01247; DKFZp686B2470; DKFZp686G18243; DKFZp686G2094; DKFZp781C1754; DKFZp781I1455; LIM and calponin homology domains-containing protein 1; LIMCH1A; LMO7B; MGC72127
Mus musculus (house mouse) : Limch1 (LIM and calponin homology domains 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Limch1 (LIM and calponin homology domains 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Limch1 (LIM and calponin homology domains 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LIMCH1 (LIM and calponin homology domains 1)
Canis lupus familiaris (dog) : LIMCH1 (LIM and calponin homology domains 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Limch1 (LIM and calponin homology domains 1)
Sus scrofa (pig) : LIMCH1 (LIM and calponin homology domains 1)
Chlorocebus sabaeus (African green monkey) : LIMCH1 (LIM and calponin homology domains 1)
Heterocephalus glaber (naked mole-rat) : Limch1 (LIM and calponin homology domains 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl441,359,607 - 41,700,044 (+)EnsemblGRCh38hg38GRCh38
GRCh38441,359,607 - 41,700,044 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37441,362,802 - 41,702,061 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36441,057,561 - 41,395,767 (+)NCBINCBI36hg18NCBI36
Celera441,806,095 - 42,146,075 (+)NCBI
Cytogenetic Map4p13NCBI
HuRef440,684,478 - 41,024,427 (+)NCBIHuRef
CHM1_1441,362,176 - 41,702,595 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on LIMCH1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604823
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-07-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.