 Gene-Chemical Interaction Annotations | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Analyze GeneStrainQTL List |
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Disease Annotations
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Gene-Chemical Interaction Annotations
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References - curatedReferences - uncuratedGenomics
Comparative Map Data| WDR86 (Homo sapiens - human) |
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| Wdr86 (Mus musculus - house mouse) |
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| Wdr86 (Rattus norvegicus - Norway rat) |
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| Wdr86 (Chinchilla lanigera - long-tailed chinchilla) |
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| WDR86 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| WDR86 (Canis lupus familiaris - dog) |
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| Wdr86 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| WDR86 (Sus scrofa - pig) |
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Position Markers| SHGC-132944 |
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| SHGC-57659 |
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| D7S2841 |
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| GDB:4585257 |
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| GDB:4585553 |
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miRNA Target Status
Predicted Target Of
| The detailed report is available here: |  | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_001284260 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| NM_001284261 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| NM_001284262 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| NM_198285 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_005249989 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_005249990 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006715966 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_011516144 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_011516145 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_011516146 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_011516147 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_011516148 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_011516150 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_011516151 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_011516152 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AACC02000108 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AC005486 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AC005996 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AK096225 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AK125347 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AK296049 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AK301628 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC047921 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC107125 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BI757623 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BX338490 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BX390499 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH471173 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| DA267732 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | NM_001284260 ⟹ NP_001271189 | |||||||||||||||||||
| RefSeq Status: | VALIDATED | |||||||||||||||||||
| Type: | CODING | |||||||||||||||||||
| Position: |
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| Sequence: |
ACCGTATTGTTCCGCGCTCGGCCGGGGAGGGCGCGGGGCGCTCGGCTTCCCGTGTTCCTCTCCChide sequence |
| RefSeq Acc Id: | NM_001284261 ⟹ NP_001271190 | |||||||||||||||||||
| RefSeq Status: | VALIDATED | |||||||||||||||||||
| Type: | CODING | |||||||||||||||||||
| Position: |
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| Sequence: |
GCGCCGGAACTGCCCTAATGGAAACCAGCCGCCGGGCGCTCCGGGAGGGCTCAGGCCGACCCCGhide sequence |
| RefSeq Acc Id: | NM_001284262 ⟹ NP_001271191 | |||||||||||||||||||
| RefSeq Status: | VALIDATED | |||||||||||||||||||
| Type: | CODING | |||||||||||||||||||
| Position: |
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| Sequence: |
GCGCCGGAACTGCCCTAATGGAAACCAGCCGCCGGGCGCTCCGGGAGGGCTCAGGCCGACCCCGhide sequence |
| RefSeq Acc Id: | NM_198285 ⟹ NP_938026 | |||||||||||||||||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | |||||||||||||||||||||||||||||||||||||||
| Type: | CODING | |||||||||||||||||||||||||||||||||||||||
| Position: |
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| Sequence: |
ACCGTATTGTTCCGCGCTCGGCCGGGGAGGGCGCGGGGCGCTCGGCTTCCCGTGTTCCTCTCCChide sequence |
| RefSeq Acc Id: | XM_005249989 ⟹ XP_005250046 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
GTGGATCCTCCGAGCGGTGCTGGGAAGGGGGTTCTCTCTGCCCGCGCGCCCAGGACTCTACCCAhide sequence |
| RefSeq Acc Id: | XM_005249990 ⟹ XP_005250047 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GTGGATCCTCCGAGCGGTGCTGGGAAGGGGGTTCTCTCTGCCCGCGCGCCCAGGACTCTACCCAhide sequence |
| RefSeq Acc Id: | XM_006715966 ⟹ XP_006716029 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GTGGATCCTCCGAGCGGTGCTGGGAAGGGGGTTCTCTCTGCCCGCGCGCCCAGGACTCTACCCAhide sequence |
| RefSeq Acc Id: | XM_011516144 ⟹ XP_011514446 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GTGGATCCTCCGAGCGGTGCTGGGAAGGGGGTTCTCTCTGCCCGCGCGCCCAGGACTCTACCCAhide sequence |
| RefSeq Acc Id: | XM_011516145 ⟹ XP_011514447 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GTGGATCCTCCGAGCGGTGCTGGGAAGGGGGTTCTCTCTGCCCGCGCGCCCAGGACTCTACCCAhide sequence |
| RefSeq Acc Id: | XM_011516146 ⟹ XP_011514448 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GTGGATCCTCCGAGCGGTGCTGGGAAGGGGGTTCTCTCTGCCCGCGCGCCCAGGACTCTACCCAhide sequence |
| RefSeq Acc Id: | XM_011516147 ⟹ XP_011514449 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GTGGATCCTCCGAGCGGTGCTGGGAAGGGGGTTCTCTCTGCCCGCGCGCCCAGGACTCTACCCAhide sequence |
| RefSeq Acc Id: | XM_011516148 ⟹ XP_011514450 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
AATGGAAACCAGCCGCCGGGCGCTCCGGGAGGGCTCAGGCCGACCCCGGGGTCCATTAGAGGCGhide sequence |
| RefSeq Acc Id: | XM_011516150 ⟹ XP_011514452 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
CGGCCCCAGACCGCGGACCCCAGCTCCTGCGCCCGCAGACCCCTTTCTAGAAGTCCAGCCCCCGhide sequence |
| RefSeq Acc Id: | XM_011516151 ⟹ XP_011514453 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GTGGATCCTCCGAGCGGTGCTGGGAAGGGGGTTCTCTCTGCCCGCGCGCCCAGGACTCTACCCAhide sequence |
| RefSeq Acc Id: | XM_011516152 ⟹ XP_011514454 | |||||||||
| RefSeq Status: | ||||||||||
| Type: | CODING | |||||||||
| Position: |
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| Sequence: |
GTGGATCCTCCGAGCGGTGCTGGGAAGGGGGTTCTCTCTGCCCGCGCGCCCAGGACTCTACCCAhide sequence |
Protein Sequences| Protein RefSeqs | NP_001271189 | (Get FASTA) | NCBI Sequence Viewer |
| NP_001271190 | (Get FASTA) | NCBI Sequence Viewer | |
| NP_001271191 | (Get FASTA) | NCBI Sequence Viewer | |
| NP_938026 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_005250046 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_005250047 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006716029 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_011514446 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_011514447 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_011514448 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_011514449 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_011514450 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_011514452 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_011514453 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_011514454 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAI07126 | (Get FASTA) | NCBI Sequence Viewer |
| BAC86140 | (Get FASTA) | NCBI Sequence Viewer | |
| BAG58813 | (Get FASTA) | NCBI Sequence Viewer | |
| BAG63113 | (Get FASTA) | NCBI Sequence Viewer | |
| EAL24513 | (Get FASTA) | NCBI Sequence Viewer | |
| EAW53995 | (Get FASTA) | NCBI Sequence Viewer | |
| EAW53996 | (Get FASTA) | NCBI Sequence Viewer | |
| EAW53997 | (Get FASTA) | NCBI Sequence Viewer | |
| EAW53998 | (Get FASTA) | NCBI Sequence Viewer | |
| Q86TI4 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_938026 ⟸ NM_198285 |
| - Peptide Label: | isoform 2 |
| - UniProtKB: | Q86TI4 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MGGGGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQCCALLQGHESYVTFCQhide sequence |
| RefSeq Acc Id: | XP_005250047 ⟸ XM_005249990 |
| - Peptide Label: | isoform X7 |
| - Sequence: |
MGGGGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQCCALLQGHESYVTFCQhide sequence |
| RefSeq Acc Id: | XP_005250046 ⟸ XM_005249989 |
| - Peptide Label: | isoform X3 |
| - Sequence: |
MGGGGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQCCALLQGHESYVTFCQhide sequence |
| RefSeq Acc Id: | NP_001271190 ⟸ NM_001284261 |
| - Peptide Label: | isoform 3 |
| - UniProtKB: | Q86TI4 (UniProtKB/Swiss-Prot), A0A090N7X3 (UniProtKB/TrEMBL) |
| - Sequence: |
MSREFRGHRNCVLTLAYSAPWDLPSTPCAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHhide sequence |
| RefSeq Acc Id: | NP_001271191 ⟸ NM_001284262 |
| - Peptide Label: | isoform 4 |
| - UniProtKB: | Q86TI4 (UniProtKB/Swiss-Prot), A0A0C4DGX6 (UniProtKB/TrEMBL) |
| - Sequence: |
MSREFRGHRNCVLTLAYSAPWDLPSTPCAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHhide sequence |
| RefSeq Acc Id: | NP_001271189 ⟸ NM_001284260 |
| - Peptide Label: | isoform 1 |
| - UniProtKB: | Q86TI4 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MGGGGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQCCALLQGHESYVTFCQhide sequence |
| RefSeq Acc Id: | XP_006716029 ⟸ XM_006715966 |
| - Peptide Label: | isoform X8 |
| - Sequence: |
MGGGGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQCCALLQGHESYVTFCQhide sequence |
| RefSeq Acc Id: | XP_011514453 ⟸ XM_011516151 |
| - Peptide Label: | isoform X9 |
| - Sequence: |
MGGGGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQCCALLQGHESYVTFCQhide sequence |
| RefSeq Acc Id: | XP_011514449 ⟸ XM_011516147 |
| - Peptide Label: | isoform X5 |
| - Sequence: |
MGGGGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQCCALLQGHESYVTFCQhide sequence |
| RefSeq Acc Id: | XP_011514447 ⟸ XM_011516145 |
| - Peptide Label: | isoform X2 |
| - Sequence: |
MGGGGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQCCALLQGHESYVTFCQhide sequence |
| RefSeq Acc Id: | XP_011514446 ⟸ XM_011516144 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MGGGGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQCCALLQGHESYVTFCQhide sequence |
| RefSeq Acc Id: | XP_011514448 ⟸ XM_011516146 |
| - Peptide Label: | isoform X4 |
| - Sequence: |
MGGGGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQCCALLQGHESYVTFCQhide sequence |
| RefSeq Acc Id: | XP_011514450 ⟸ XM_011516148 |
| - Peptide Label: | isoform X6 |
| - Sequence: |
MSREFRGHRNCVLTLAYSAPWDLPSTPCAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHhide sequence |
| RefSeq Acc Id: | XP_011514452 ⟸ XM_011516150 |
| - Peptide Label: | isoform X6 |
| - Sequence: |
MSREFRGHRNCVLTLAYSAPWDLPSTPCAEEAAAGGLLVTGSTDGTAKVWQVASGCCHQTLRGHhide sequence |
| RefSeq Acc Id: | XP_011514454 ⟸ XM_011516152 |
| - Peptide Label: | isoform X10 |
| - Sequence: |
MGGGGSALRVCADHRGGINWLSLSPDGQRLLTGSEDGTARLWSTADGQCCALLQGHESYVTFCQhide sequence |
Promoters| RGD ID: | 6813334 | |||||||||
| Promoter ID: | HG_ACW:75100 | |||||||||
| Type: | CpG-Island | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | MPROMDB | |||||||||
| Tissues & Cell Lines: | CD4+TCell_12Hour | |||||||||
| Transcripts: | SWAWSMARBU.AAPR07-UNSPLICED, WDR86.EAPR07-UNSPLICED | |||||||||
| Position: |
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Clinical Variants| Name | Type | Condition(s) | Position(s) | Clinical significance |
| GRCh38/hg38 7q32.1-36.3(chr7:129310166-159282390)x3 | copy number gain | Cleft palate, isolated [RCV000050876]|See cases [RCV000050876] | Chr7:129310166..159282390 [GRCh38] Chr7:128950007..159075079 [GRCh37] Chr7:128737243..158767840 [NCBI36] Chr7:7q32.1-36.3 |
pathogenic |
| GRCh38/hg38 7q36.1(chr7:150319864-152674271)x1 | copy number loss | Seizure [RCV000050552]|See cases [RCV000050552] | Chr7:150319864..152674271 [GRCh38] Chr7:150016953..152371356 [GRCh37] Chr7:149647886..152002289 [NCBI36] Chr7:7q36.1 |
pathogenic |
| GRCh38/hg38 7q35-36.1(chr7:143884559-152674271)x1 | copy number loss | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000050750]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000050750]|See cases [RCV000050750] | Chr7:143884559..152674271 [GRCh38] Chr7:143581652..152371356 [GRCh37] Chr7:143212585..152002289 [NCBI36] Chr7:7q35-36.1 |
pathogenic |
| GRCh38/hg38 7q32.3-36.3(chr7:132850196-159325876)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051101]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051101]|See cases [RCV000051101] | Chr7:132850196..159325876 [GRCh38] Chr7:132534956..159118566 [GRCh37] Chr7:132185496..158811327 [NCBI36] Chr7:7q32.3-36.3 |
pathogenic |
| GRCh38/hg38 7q35-36.3(chr7:147250465-159325876)x1 | copy number loss | Abnormality of the kidney [RCV000051108]|See cases [RCV000051108] | Chr7:147250465..159325876 [GRCh38] Chr7:146947557..159118566 [GRCh37] Chr7:146578490..158811327 [NCBI36] Chr7:7q35-36.3 |
pathogenic |
| GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 | copy number loss | Ambiguous genitalia [RCV000052250]|See cases [RCV000052250] | Chr7:53985..159282531 [GRCh38] Chr7:53985..159075220 [GRCh37] Chr7:149068..158767981 [NCBI36] Chr7:7p22.3-q36.3 |
pathogenic |
| GRCh38/hg38 7q33-36.3(chr7:136309982-159307523)x3 | copy number gain | Global developmental delay [RCV000053576]|See cases [RCV000053576] | Chr7:136309982..159307523 [GRCh38] Chr7:135994730..159100212 [GRCh37] Chr7:135645270..158792973 [NCBI36] Chr7:7q33-36.3 |
pathogenic |
| GRCh38/hg38 7q34-36.3(chr7:142021716-159325876)x3 | copy number gain | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053577]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053577]|See cases [RCV000053577] | Chr7:142021716..159325876 [GRCh38] Chr7:142528609..159118566 [GRCh37] Chr7:141367985..158811327 [NCBI36] Chr7:7q34-36.3 |
pathogenic |
| GRCh38/hg38 7q34-36.3(chr7:142358524-159282531)x1 | copy number loss | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054177]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054177]|See cases [RCV000054177] | Chr7:142358524..159282531 [GRCh38] Chr7:142528609..159075220 [GRCh37] Chr7:141726947..158767981 [NCBI36] Chr7:7q34-36.3 |
pathogenic |
| GRCh38/hg38 7q35-36.3(chr7:143884559-159282390)x1 | copy number loss | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054178]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054178]|See cases [RCV000054178] | Chr7:143884559..159282390 [GRCh38] Chr7:143581652..159075079 [GRCh37] Chr7:143212585..158767840 [NCBI36] Chr7:7q35-36.3 |
pathogenic |
| GRCh38/hg38 7q35-36.3(chr7:145699944-159296617)x1 | copy number loss | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054188]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054188]|See cases [RCV000054188] | Chr7:145699944..159296617 [GRCh38] Chr7:145397037..159089306 [GRCh37] Chr7:145027970..158782067 [NCBI36] Chr7:7q35-36.3 |
pathogenic |
| GRCh38/hg38 7q36.1(chr7:148256584-152332535)x1 | copy number loss | Attention deficit-hyperactivity disorder [RCV000054189]|See cases [RCV000054189] | Chr7:148256584..152332535 [GRCh38] Chr7:147953676..152029620 [GRCh37] Chr7:147584609..151660553 [NCBI36] Chr7:7q36.1 |
pathogenic |
| GRCh38/hg38 7q34-36.3(chr7:139365967-159282531)x1 | copy number loss | Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054175]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054175]|See cases [RCV000054175] | Chr7:139365967..159282531 [GRCh38] Chr7:139050713..159075220 [GRCh37] Chr7:138701253..158767981 [NCBI36] Chr7:7q34-36.3 |
pathogenic |
| GRCh38/hg38 7q34-36.3(chr7:140754198-159307523)x1 | copy number loss | Corpus callosum agenesis [RCV000054176]|See cases [RCV000054176] | Chr7:140754198..159307523 [GRCh38] Chr7:140453998..159100212 [GRCh37] Chr7:140100467..158792973 [NCBI36] Chr7:7q34-36.3 |
pathogenic |
| GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 | copy number loss | See cases [RCV000135401] | Chr7:54185..159282390 [GRCh38] Chr7:54185..159075079 [GRCh37] Chr7:149268..158767840 [NCBI36] Chr7:7p22.3-q36.3 |
pathogenic |
| GRCh38/hg38 7q36.1-36.2(chr7:151214163-153187462)x1 | copy number loss | See cases [RCV000134853] | Chr7:151214163..153187462 [GRCh38] Chr7:150911249..152884547 [GRCh37] Chr7:150542182..152515480 [NCBI36] Chr7:7q36.1-36.2 |
pathogenic |
| GRCh38/hg38 7q35-36.2(chr7:147345844-153833351)x3 | copy number gain | See cases [RCV000135825] | Chr7:147345844..153833351 [GRCh38] Chr7:147042936..153530436 [GRCh37] Chr7:146673869..153161369 [NCBI36] Chr7:7q35-36.2 |
pathogenic |
| GRCh38/hg38 7q36.1-36.3(chr7:151378879-158923762)x1 | copy number loss | See cases [RCV000136125] | Chr7:151378879..158923762 [GRCh38] Chr7:151075965..158716453 [GRCh37] Chr7:150706898..158409214 [NCBI36] Chr7:7q36.1-36.3 |
pathogenic|benign |
| GRCh38/hg38 7q33-36.2(chr7:137751200-154815582)x3 | copy number gain | See cases [RCV000136592] | Chr7:137751200..154815582 [GRCh38] Chr7:137435946..154607292 [GRCh37] Chr7:137086486..154238225 [NCBI36] Chr7:7q33-36.2 |
pathogenic |
| GRCh38/hg38 7q36.1-36.3(chr7:150486071-159335865)x1 | copy number loss | See cases [RCV000136089] | Chr7:150486071..159335865 [GRCh38] Chr7:150183159..159128555 [GRCh37] Chr7:149814092..158821316 [NCBI36] Chr7:7q36.1-36.3 |
pathogenic |
| GRCh38/hg38 7q21.3-36.3(chr7:97419852-158923762)x3 | copy number gain | See cases [RCV000136717] | Chr7:97419852..158923762 [GRCh38] Chr7:97049164..158716453 [GRCh37] Chr7:96887100..158409214 [NCBI36] Chr7:7q21.3-36.3 |
pathogenic |
| GRCh38/hg38 7q36.1-36.3(chr7:151104277-159325876)x3 | copy number gain | See cases [RCV000136683] | Chr7:151104277..159325876 [GRCh38] Chr7:150801364..159118566 [GRCh37] Chr7:150432297..158811327 [NCBI36] Chr7:7q36.1-36.3 |
pathogenic |
| GRCh38/hg38 7q36.1-36.3(chr7:150802801-159335866)x1 | copy number loss | See cases [RCV000137465] | Chr7:150802801..159335866 [GRCh38] Chr7:150499889..159128556 [GRCh37] Chr7:150130822..158821317 [NCBI36] Chr7:7q36.1-36.3 |
pathogenic |
| GRCh38/hg38 7q34-36.3(chr7:141960861-159335866)x1 | copy number loss | See cases [RCV000137256] | Chr7:141960861..159335866 [GRCh38] Chr7:142528609..159128556 [GRCh37] Chr7:141307130..158821317 [NCBI36] Chr7:7q34-36.3 |
pathogenic |
| GRCh38/hg38 7q35-36.3(chr7:145436544-159331441)x1 | copy number loss | See cases [RCV000137338] | Chr7:145436544..159331441 [GRCh38] Chr7:145133637..159124131 [GRCh37] Chr7:144764570..158816892 [NCBI36] Chr7:7q35-36.3 |
pathogenic|likely pathogenic |
| GRCh38/hg38 7q35-36.3(chr7:145250254-159335866)x1 | copy number loss | See cases [RCV000138005] | Chr7:145250254..159335866 [GRCh38] Chr7:144947347..159128556 [GRCh37] Chr7:144578280..158821317 [NCBI36] Chr7:7q35-36.3 |
pathogenic |
| GRCh38/hg38 7q33-36.3(chr7:134666829-158591882)x1 | copy number loss | See cases [RCV000138120] | Chr7:134666829..158591882 [GRCh38] Chr7:134351581..158384574 [GRCh37] Chr7:134002121..158077335 [NCBI36] Chr7:7q33-36.3 |
pathogenic |
| GRCh38/hg38 7q35-36.3(chr7:146047157-157522158)x1 | copy number loss | See cases [RCV000137781] | Chr7:146047157..157522158 [GRCh38] Chr7:145744250..157314852 [GRCh37] Chr7:145375183..157007613 [NCBI36] Chr7:7q35-36.3 |
pathogenic |
| GRCh38/hg38 7q31.32-36.3(chr7:121863759-159335865)x3 | copy number gain | See cases [RCV000138847] | Chr7:121863759..159335865 [GRCh38] Chr7:121503813..159128555 [GRCh37] Chr7:121291049..158821316 [NCBI36] Chr7:7q31.32-36.3 |
pathogenic |
| GRCh38/hg38 7q36.1-36.2(chr7:150113232-154162779)x3 | copy number gain | See cases [RCV000138566] | Chr7:150113232..154162779 [GRCh38] Chr7:149810321..153859864 [GRCh37] Chr7:149441254..153490797 [NCBI36] Chr7:7q36.1-36.2 |
likely pathogenic |
| GRCh38/hg38 7q32.3-36.3(chr7:132444095-159335866)x3 | copy number gain | See cases [RCV000139654] | Chr7:132444095..159335866 [GRCh38] Chr7:132128854..159128556 [GRCh37] Chr7:131779394..158821317 [NCBI36] Chr7:7q32.3-36.3 |
pathogenic |
| GRCh38/hg38 7q36.1-36.2(chr7:150275734-153342804)x3 | copy number gain | See cases [RCV000139660] | Chr7:150275734..153342804 [GRCh38] Chr7:149972823..153039889 [GRCh37] Chr7:149603756..152670822 [NCBI36] Chr7:7q36.1-36.2 |
uncertain significance |
| GRCh38/hg38 7q31.2-36.3(chr7:115459015-159325817)x3 | copy number gain | See cases [RCV000141413] | Chr7:115459015..159325817 [GRCh38] Chr7:115099069..159118507 [GRCh37] Chr7:114886305..158811268 [NCBI36] Chr7:7q31.2-36.3 |
pathogenic |
| GRCh38/hg38 7q32.3-36.3(chr7:131228764-159335866)x3 | copy number gain | See cases [RCV000142802] | Chr7:131228764..159335866 [GRCh38] Chr7:130913523..159128556 [GRCh37] Chr7:130564063..158821317 [NCBI36] Chr7:7q32.3-36.3 |
pathogenic |
| GRCh38/hg38 7q36.1-36.3(chr7:150260297-159325876)x1 | copy number loss | See cases [RCV000142592] | Chr7:150260297..159325876 [GRCh38] Chr7:149957386..159118566 [GRCh37] Chr7:149588319..158811327 [NCBI36] Chr7:7q36.1-36.3 |
pathogenic |
| GRCh38/hg38 7q32.3-36.3(chr7:131171478-159327017)x3 | copy number gain | See cases [RCV000143754] | Chr7:131171478..159327017 [GRCh38] Chr7:130856237..159119707 [GRCh37] Chr7:130506777..158812468 [NCBI36] Chr7:7q32.3-36.3 |
pathogenic |
| GRCh38/hg38 7q32.3-36.3(chr7:132438072-159327017)x3 | copy number gain | See cases [RCV000143707] | Chr7:132438072..159327017 [GRCh38] Chr7:132122831..159119707 [GRCh37] Chr7:131773371..158812468 [NCBI36] Chr7:7q32.3-36.3 |
pathogenic |
| GRCh38/hg38 7q35-36.3(chr7:147144002-159327017)x1 | copy number loss | See cases [RCV000143503] | Chr7:147144002..159327017 [GRCh38] Chr7:146841094..159119707 [GRCh37] Chr7:146472027..158812468 [NCBI36] Chr7:7q35-36.3 |
pathogenic |
| GRCh37/hg19 7p22.3-q36.3(chr7:43360-159119707)x1 | copy number loss | See cases [RCV000446044] | Chr7:43360..159119707 [GRCh37] Chr7:7p22.3-q36.3 |
pathogenic |
| GRCh37/hg19 7q33-36.3(chr7:137589621-159119707)x3 | copy number gain | See cases [RCV000449264] | Chr7:137589621..159119707 [GRCh37] Chr7:7q33-36.3 |
pathogenic |
| Single allele | copy number loss | Abnormality of esophagus morphology [RCV000416719]|Abnormality of the esophagus [RCV000416719] | Chr7:143839360..159138663 [GRCh37] | pathogenic |
| GRCh37/hg19 7q22.1-36.3(chr7:98969247-159119707)x3 | copy number gain | See cases [RCV000447709] | Chr7:98969247..159119707 [GRCh37] Chr7:7q22.1-36.3 |
pathogenic |
| GRCh37/hg19 7q33-36.3(chr7:133799185-159119707)x1 | copy number loss | See cases [RCV000448836] | Chr7:133799185..159119707 [GRCh37] Chr7:7q33-36.3 |
pathogenic |
| GRCh37/hg19 7q36.1-36.3(chr7:149261179-159075020)x3 | copy number gain | See cases [RCV000447776] | Chr7:149261179..159075020 [GRCh37] Chr7:7q36.1-36.3 |
pathogenic |
| GRCh37/hg19 7q32.1-36.3(chr7:128276078-159119707)x3 | copy number gain | See cases [RCV000447956] | Chr7:128276078..159119707 [GRCh37] Chr7:7q32.1-36.3 |
pathogenic |
| GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707) | copy number gain | See cases [RCV000510686] | Chr7:43361..159119707 [GRCh37] Chr7:7p22.3-q36.3 |
pathogenic |
| GRCh37/hg19 7q34-36.3(chr7:140636858-159119707)x1 | copy number loss | See cases [RCV000510250] | Chr7:140636858..159119707 [GRCh37] Chr7:7q34-36.3 |
pathogenic |
| GRCh37/hg19 7q33-36.3(chr7:136758593-159119707)x3 | copy number gain | See cases [RCV000510490] | Chr7:136758593..159119707 [GRCh37] Chr7:7q33-36.3 |
pathogenic |
| GRCh37/hg19 7q33-36.3(chr7:137917376-159119707)x1 | copy number loss | See cases [RCV000511889] | Chr7:137917376..159119707 [GRCh37] Chr7:7q33-36.3 |
pathogenic |
| GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707)x3 | copy number gain | See cases [RCV000511549] | Chr7:43361..159119707 [GRCh37] Chr7:7p22.3-q36.3 |
pathogenic |
| GRCh37/hg19 7q36.1-36.3(chr7:150553743-159119707)x3 | copy number gain | See cases [RCV000510762] | Chr7:150553743..159119707 [GRCh37] Chr7:7q36.1-36.3 |
likely pathogenic |
| NC_000007.13:g.(?_150642433)_(151573725_?)del | deletion | Long QT syndrome [RCV000631876] | Chr7:150642433..151573725 [GRCh37] Chr7:7q36.1 |
pathogenic |
| GRCh37/hg19 7q34-36.3(chr7:140133025-158982771)x1 | copy number loss | not provided [RCV000682910] | Chr7:140133025..158982771 [GRCh37] Chr7:7q34-36.3 |
pathogenic |
| GRCh37/hg19 7q22.1-36.3(chr7:98693388-159119707)x3 | copy number gain | not provided [RCV000682911] | Chr7:98693388..159119707 [GRCh37] Chr7:7q22.1-36.3 |
pathogenic |
| GRCh37/hg19 7p22.3-q36.3(chr7:44935-159126310)x3 | copy number gain | not provided [RCV000746280] | Chr7:44935..159126310 [GRCh37] Chr7:7p22.3-q36.3 |
pathogenic |
| GRCh37/hg19 7p22.3-q36.3(chr7:10704-159122532)x3 | copy number gain | not provided [RCV000746278] | Chr7:10704..159122532 [GRCh37] Chr7:7p22.3-q36.3 |
pathogenic |
| GRCh37/hg19 7q34-36.3(chr7:139623170-158329903)x3 | copy number gain | not provided [RCV000747070] | Chr7:139623170..158329903 [GRCh37] Chr7:7q34-36.3 |
pathogenic |
| GRCh37/hg19 7q34-36.3(chr7:141938235-159126310)x1 | copy number loss | not provided [RCV000747083] | Chr7:141938235..159126310 [GRCh37] Chr7:7q34-36.3 |
pathogenic |
| GRCh37/hg19 7q35-36.1(chr7:143711059-152573935)x3 | copy number gain | not provided [RCV000747094] | Chr7:143711059..152573935 [GRCh37] Chr7:7q35-36.1 |
benign |
| GRCh37/hg19 7q36.1-36.3(chr7:148238976-159126310)x1 | copy number loss | not provided [RCV000747115] | Chr7:148238976..159126310 [GRCh37] Chr7:7q36.1-36.3 |
pathogenic |
| GRCh37/hg19 7p22.3-q36.3(chr7:10365-159119707)x3 | copy number gain | not provided [RCV000848126] | Chr7:10365..159119707 [GRCh37] Chr7:7p22.3-q36.3 |
pathogenic |
| GRCh37/hg19 7q32.1-36.3(chr7:128312450-159119220) | copy number gain | not provided [RCV000767558] | Chr7:128312450..159119220 [GRCh37] Chr7:7q32.1-36.3 |
pathogenic |
| GRCh37/hg19 7q32.3-36.3(chr7:130592554-159119707)x3 | copy number gain | not provided [RCV000849569] | Chr7:130592554..159119707 [GRCh37] Chr7:7q32.3-36.3 |
pathogenic |
| GRCh37/hg19 7q36.1(chr7:149968222-152539376)x3 | copy number gain | not provided [RCV000847582] | Chr7:149968222..152539376 [GRCh37] Chr7:7q36.1 |
uncertain significance |
Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | HGNC:28020 | AgrOrtholog |
| COSMIC | WDR86 | COSMIC |
| Ensembl Genes | ENSG00000187260 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSP00000335522 | ENTREZGENE, UniProtKB/Swiss-Prot |
| ENSP00000417512 | ENTREZGENE, UniProtKB/Swiss-Prot | |
| ENSP00000419162 | ENTREZGENE, UniProtKB/Swiss-Prot | |
| ENSP00000482209 | ENTREZGENE, UniProtKB/TrEMBL | |
| ENSP00000486705 | UniProtKB/Swiss-Prot | |
| Ensembl Transcript | ENST00000334493 | ENTREZGENE, UniProtKB/Swiss-Prot |
| ENST00000469830 | ENTREZGENE, UniProtKB/Swiss-Prot | |
| ENST00000477459 | ENTREZGENE, UniProtKB/Swiss-Prot | |
| ENST00000621812 | ENTREZGENE, UniProtKB/TrEMBL | |
| ENST00000628331 | UniProtKB/Swiss-Prot | |
| Gene3D-CATH | 2.130.10.10 | UniProtKB/Swiss-Prot |
| GTEx | ENSG00000187260 | GTEx |
| HGNC ID | HGNC:28020 | ENTREZGENE |
| Human Proteome Map | WDR86 | Human Proteome Map |
| InterPro | G-protein_beta_WD-40_rep | UniProtKB/Swiss-Prot |
| Quinoprotein_ADH-like_supfam | UniProtKB/Swiss-Prot | |
| WD40/YVTN_repeat-like_dom_sf | UniProtKB/Swiss-Prot | |
| WD40_repeat | UniProtKB/Swiss-Prot | |
| WD40_repeat_CS | UniProtKB/Swiss-Prot | |
| WD40_repeat_dom | UniProtKB/Swiss-Prot | |
| WD40_repeat_dom_sf | UniProtKB/Swiss-Prot | |
| KEGG Report | hsa:349136 | UniProtKB/Swiss-Prot |
| NCBI Gene | 349136 | ENTREZGENE |
| Pfam | WD40 | UniProtKB/Swiss-Prot |
| PharmGKB | PA145147619 | PharmGKB |
| PRINTS | GPROTEINBRPT | UniProtKB/Swiss-Prot |
| PROSITE | WD_REPEATS_1 | UniProtKB/Swiss-Prot |
| WD_REPEATS_2 | UniProtKB/Swiss-Prot | |
| WD_REPEATS_REGION | UniProtKB/Swiss-Prot | |
| SMART | WD40 | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | SSF50978 | UniProtKB/Swiss-Prot |
| SSF50998 | UniProtKB/Swiss-Prot | |
| UniGene | Hs.647083 | ENTREZGENE |
| Hs.659458 | ENTREZGENE | |
| UniProt | A0A090N7X3 | ENTREZGENE, UniProtKB/TrEMBL |
| A0A0C4DGX6 | ENTREZGENE, UniProtKB/TrEMBL | |
| Q86TI4 | ENTREZGENE, UniProtKB/Swiss-Prot | |
| UniProt Secondary | B4DJF1 | UniProtKB/Swiss-Prot |
| C9JAJ5 | UniProtKB/Swiss-Prot | |
| C9JXE3 | UniProtKB/Swiss-Prot | |
| Q3KNT1 | UniProtKB/Swiss-Prot | |
| Q6ZUS8 | UniProtKB/Swiss-Prot |
 |
| More on WDR86 | |
|
Alliance Gene |
|
NCBI Gene |
|
Ensembl Gene |
|
|
JBrowse: hg19 hg38 |
|
HGNC Report |
|
NCBI Genome Data Viewer |
| CRRD Object Information | |
| CRRD ID: | 1604947 |
| Created: | 2007-04-28 |
| Species: | Homo sapiens |
| Last Modified: | 2019-11-26 |
| Status: | ACTIVE |
