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Gene: MAPK15 (mitogen-activated protein kinase 15) Homo sapiens
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Symbol: MAPK15
Name: mitogen-activated protein kinase 15
Description: Exhibits MAP kinase activity and chromatin binding activity. Involved in several processes, including dopamine uptake; positive regulation of DNA metabolic process; and regulation of organelle organization. Localizes to several cellular components, including Golgi apparatus; autophagosome; and microtubule organizing center. Biomarker of breast cancer; INTERACTS WITH atrazine; bis(2-ethylhexyl) phthalate; copper atom.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ERK-7; ERK-8; ERK7; ERK8; extracellular regulated kinase 8 delta; extracellular signal regulated kinase 8; extracellular signal-regulated kinase 7; extracellular signal-regulated kinase 8; MAP kinase 15; MAPK 15
Orthologs:
Mus musculus (house mouse) : Mapk15 (mitogen-activated protein kinase 15)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mapk15 (mitogen-activated protein kinase 15)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk15 (mitogen-activated protein kinase 15)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK15 (mitogen-activated protein kinase 15)
Canis lupus familiaris (dog) : MAPK15 (mitogen-activated protein kinase 15)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk15 (mitogen-activated protein kinase 15)
Sus scrofa (pig) : MAPK15 (mitogen-activated protein kinase 15)
Chlorocebus sabaeus (African green monkey) : MAPK15 (mitogen-activated protein kinase 15)
Heterocephalus glaber (naked mole-rat) : Mapk15 (mitogen-activated protein kinase 15)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl8143,716,340 - 143,722,458 (+)EnsemblGRCh38hg38GRCh38
GRCh388143,716,305 - 143,722,458 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh378144,798,507 - 144,804,633 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368144,870,495 - 144,876,621 (+)NCBINCBI36hg18NCBI36
Celera8141,109,455 - 141,115,595 (+)NCBI
Cytogenetic Map8q24.3NCBI
HuRef8140,051,333 - 140,057,442 (+)NCBIHuRef
CHM1_18144,838,551 - 144,844,676 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MAPK15
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1604966
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.