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Gene: ERI1 (exoribonuclease 1) Homo sapiens
Symbol: ERI1
Name: exoribonuclease 1
Description: Exhibits 3'-5' exonuclease activity. Predicted to be involved in DNA catabolic process, exonucleolytic and exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Localizes to cytoplasm and nucleolus; PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3' exoribonuclease; 3'-5' exonuclease ERI1; 3'-5' exoribonuclease 1; 3'HEXO; enhanced RNAi three prime mRNA exonuclease homolog 1; Eri-1 homolog; HEXO; histone mRNA 3' end-specific exonuclease; histone mRNA 3'-end-specific exoribonuclease; histone mRNA 3'-exonuclease 1; MGC35395; THEX1; three prime histone mRNA exonuclease 1; three prime mRNA exonuclease 1
Mus musculus (house mouse) : Eri1 (exoribonuclease 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Eri1 (exoribonuclease 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eri1 (exoribonuclease 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ERI1 (exoribonuclease 1)
Canis lupus familiaris (dog) : ERI1 (exoribonuclease 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Eri1 (exoribonuclease 1)
Sus scrofa (pig) : ERI1 (exoribonuclease 1)
Chlorocebus sabaeus (African green monkey) : ERI1 (exoribonuclease 1)
Heterocephalus glaber (naked mole-rat) : Eri1 (exoribonuclease 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl89,002,147 - 9,116,746 (+)EnsemblGRCh38hg38GRCh38
GRCh3888,892,225 - 9,100,262 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3788,860,314 - 8,890,849 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3688,897,860 - 8,925,899 (+)NCBINCBI36hg18NCBI36
Celera87,988,552 - 8,019,088 (+)NCBI
Cytogenetic Map8p23.1NCBI
HuRef87,785,390 - 7,815,914 (+)NCBIHuRef
CHM1_188,925,749 - 8,956,251 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ERI1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605015
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.