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Gene: IMPACT (impact RWD domain protein) Homo sapiens
Symbol: IMPACT
Name: impact RWD domain protein
Description: Predicted to have actin binding activity and ribosome binding activity. Predicted to be involved in several processes, including cellular response to starvation; generation of neurons; and negative regulation of nitrogen compound metabolic process. Predicted to localize to the polysome; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; cadmium atom; cyclosporin A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Impact homolog; imprinted and ancient gene protein homolog; MGC33718; RWD domain containing 5; RWDD5
Mus musculus (house mouse) : Impact (impact, RWD domain protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Impact (impact RWD domain protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Impact (impact RWD domain protein)
Pan paniscus (bonobo/pygmy chimpanzee) : IMPACT (impact RWD domain protein)
Canis lupus familiaris (dog) : IMPACT (impact RWD domain protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Impact (impact RWD domain protein)
Sus scrofa (pig) : IMPACT (impact RWD domain protein)
Chlorocebus sabaeus (African green monkey) : IMPACT (impact RWD domain protein)
Heterocephalus glaber (naked mole-rat) : Impact (impact RWD domain protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1824,426,634 - 24,453,531 (+)EnsemblGRCh38hg38GRCh38
GRCh381824,426,670 - 24,453,531 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371822,006,609 - 22,033,499 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361820,260,680 - 20,287,490 (+)NCBINCBI36hg18NCBI36
Celera1818,821,663 - 18,848,543 (+)NCBI
Cytogenetic Map18q11.2NCBI
HuRef1818,862,705 - 18,889,562 (+)NCBIHuRef
CHM1_11821,933,622 - 21,960,504 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IMPACT
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605062
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.