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Gene: LGR5 (leucine rich repeat containing G protein-coupled receptor 5) Homo sapiens
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Symbol: LGR5
Name: leucine rich repeat containing G protein-coupled receptor 5
Description: Exhibits transmembrane signaling receptor activity. Involved in positive regulation of canonical Wnt signaling pathway. Localizes to the integral component of plasma membrane and trans-Golgi network membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FEX; G protein-coupled receptor 49; G protein-coupled receptor 67; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; GPR49; GPR67; GRP49; HG38; leucine-rich repeat containing G protein-coupled receptor 5; leucine-rich repeat-containing G protein-coupled receptor 5; leucine-rich repeat-containing G-protein coupled receptor 5; MGC117008; orphan G protein-coupled receptor HG38
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381271,439,798 - 71,586,310 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371271,832,931 - 71,980,090 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361270,120,080 - 70,264,889 (+)NCBINCBI36hg18NCBI36
Celera1271,496,570 - 71,640,955 (+)NCBI
Cytogenetic Map12q21.1NCBI
HuRef1268,883,082 - 69,029,217 (+)NCBIHuRef
CHM1_11271,801,182 - 71,947,319 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on LGR5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605118
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.