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Gene: EPHB2 (EPH receptor B2) Homo sapiens
Symbol: EPHB2
Name: EPH receptor B2
Description: Predicted to have amyloid-beta binding activity and transmembrane-ephrin receptor activity. Involved in regulation of blood coagulation. Localizes to nucleoplasm and plasma membrane. Implicated in blood platelet disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BDPLT22; CAPB; developmentally-regulated Eph-related tyrosine kinase; DRT; EK5; elk-related tyrosine kinase; eph tyrosine kinase 3; EPH-like kinase 5; ephrin type-B receptor 2; EPHT3; ERK; Hek5; MGC87492; PCBC; protein-tyrosine kinase HEK5; renal carcinoma antigen NY-REN-47; Tyro5; tyrosine-protein kinase receptor EPH-3; tyrosine-protein kinase TYRO5
Mus musculus (house mouse) : Ephb2 (Eph receptor B2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ephb2 (Eph receptor B2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ephb2 (EPH receptor B2)
Pan paniscus (bonobo/pygmy chimpanzee) : EPHB2 (EPH receptor B2)
Canis lupus familiaris (dog) : EPHB2 (EPH receptor B2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ephb2 (EPH receptor B2)
Sus scrofa (pig) : EPHB2 (EPH receptor B2)
Chlorocebus sabaeus (African green monkey) : EPHB2 (EPH receptor B2)
Heterocephalus glaber (naked mole-rat) : Ephb2 (EPH receptor B2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl122,710,839 - 22,921,500 (+)EnsemblGRCh38hg38GRCh38
GRCh38122,710,770 - 22,921,500 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37123,037,263 - 23,241,823 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,909,918 - 23,114,410 (+)NCBINCBI36hg18NCBI36
Celera121,361,651 - 21,563,983 (+)NCBI
Cytogenetic Map1p36.12NCBI
HuRef121,351,920 - 21,485,793 (+)NCBIHuRef
CHM1_1123,149,831 - 23,360,325 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on EPHB2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605126
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.