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Gene: C4B (complement C4B (Chido blood group)) Homo sapiens
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Symbol: C4B
Name: complement C4B (Chido blood group)
Description: Exhibits carbohydrate binding activity and complement component C1q binding activity. Involved in complement activation; detection of molecule of bacterial origin; and positive regulation of apoptotic cell clearance. Localizes to several cellular components, including the dendrite; neuronal cell body; and other organism cell. Implicated in autistic disorder; autoimmune hypersensitivity disease (multiple); complement component 4b deficiency; renal cell carcinoma; and rheumatoid arthritis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: basic C4; basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; C4B1; C4B12; C4B2; C4B3; C4B5; C4B_2; C4BD; C4F; CH; Chido form of C4; CO4; complement C4-B; complement C4B1a; complement component 4B (Chido blood group); CPAMD3; FLJ60561; MGC164979
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,014,795 - 32,035,418 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37631,982,572 - 32,003,195 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36632,057,813 - 32,078,435 (+)NCBINCBI36hg18NCBI36
Celera633,549,596 - 33,570,219 (+)NCBI
Cytogenetic Map6p21.33NCBI
CHM1_1631,984,848 - 32,005,386 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on C4B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605129
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.