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Gene: PEF1 (penta-EF-hand domain containing 1) Homo sapiens
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Symbol: PEF1
Name: penta-EF-hand domain containing 1
Description: Exhibits calcium-dependent protein binding activity; protein binding activity, bridging involved in substrate recognition for ubiquitination; and protein heterodimerization activity. Involved in several processes, including COPII vesicle coating; mesenchymal cell differentiation; and positive regulation of protein monoubiquitination. Localizes to the COPII vesicle coat and Cul3-RING ubiquitin ligase complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ABP32; PEF protein with a long N-terminal hydrophobic domain; PEF1A; peflin; penta-EF hand domain containing 1; penta-EF hand domain-containing protein 1
Orthologs:
Mus musculus (house mouse) : Pef1 (penta-EF hand domain containing 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pef1 (penta-EF hand domain containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pef1 (penta-EF-hand domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PEF1 (penta-EF-hand domain containing 1)
Canis lupus familiaris (dog) : PEF1 (penta-EF-hand domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pef1 (penta-EF-hand domain containing 1)
Sus scrofa (pig) : PEF1 (penta-EF-hand domain containing 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38131,629,862 - 31,644,876 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37132,095,463 - 32,110,838 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36131,868,058 - 31,883,064 (-)NCBINCBI36hg18NCBI36
Celera130,364,685 - 30,380,064 (-)NCBI
Cytogenetic Map1p35.2NCBI
HuRef130,212,972 - 30,228,346 (-)NCBIHuRef
CHM1_1132,211,259 - 32,226,634 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PEF1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605152
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.