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Gene: LURAP1 (leucine rich adaptor protein 1) Homo sapiens
Symbol: LURAP1
Name: leucine rich adaptor protein 1
Description: Involved in positive regulation of I-kappaB kinase/NF-kappaB signaling and positive regulation of cytokine production. Localizes to the cytosol and intracellular membrane-bounded organelle; INTERACTS WITH doxorubicin; melphalan; p-chloromercuribenzoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C1orf190; FLJ25163; hypothetical protein LOC541468; leucine repeat adapter protein 35A; leucine repeat adaptor protein 35a; LRAP35a; LRP35A; NF-kappa-B activator C1orf190
Mus musculus (house mouse) : Lurap1 (leucine rich adaptor protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lurap1 (leucine rich adaptor protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lurap1 (leucine rich adaptor protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LURAP1 (leucine rich adaptor protein 1)
Canis lupus familiaris (dog) : LURAP1 (leucine rich adaptor protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lurap1 (leucine rich adaptor protein 1)
Sus scrofa (pig) : LURAP1 (leucine rich adaptor protein 1)
Chlorocebus sabaeus (African green monkey) : LURAP1 (leucine rich adaptor protein 1)
Heterocephalus glaber (naked mole-rat) : Lurap1 (leucine rich adaptor protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl146,203,334 - 46,221,256 (+)Ensembl
GRCh38146,203,334 - 46,221,256 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37146,669,006 - 46,686,928 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36146,441,593 - 46,459,746 (+)NCBINCBI36hg18NCBI36
Celera144,956,745 - 44,974,672 (+)NCBI
Cytogenetic Map1p34.1NCBI
HuRef144,783,996 - 44,802,228 (+)NCBIHuRef
CHM1_1146,786,144 - 46,804,069 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LURAP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605156
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.