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Gene: IQSEC3 (IQ motif and Sec7 domain ArfGEF 3) Homo sapiens
Symbol: IQSEC3
Name: IQ motif and Sec7 domain ArfGEF 3
Description: Predicted to have ARF guanyl-nucleotide exchange factor activity. Predicted to be involved in actin cytoskeleton organization. Localizes to the cytosol and nucleoplasm; PARTICIPATES IN endocytosis pathway; INTERACTS WITH aflatoxin B1; benzo[a]pyrene; benzo[e]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IQ motif and Sec7 domain 3; IQ motif and SEC7 domain-containing protein 3; KIAA1110; MGC30156
Mus musculus (house mouse) : Iqsec3 (IQ motif and Sec7 domain 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Iqsec3 (IQ motif and Sec7 domain ArfGEF 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Iqsec3 (IQ motif and Sec7 domain ArfGEF 3)
Pan paniscus (bonobo/pygmy chimpanzee) : IQSEC3 (IQ motif and Sec7 domain ArfGEF 3)
Canis lupus familiaris (dog) : IQSEC3 (IQ motif and Sec7 domain 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Iqsec3 (IQ motif and Sec7 domain ArfGEF 3)
Sus scrofa (pig) : IQSEC3 (IQ motif and Sec7 domain ArfGEF 3)
more info ...
Related Pseudogenes: IQSEC3P1   IQSEC3P2   IQSEC3P3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381266,767 - 178,455 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712176,049 - 287,626 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,803 - 150,755 (+)NCBINCBI36hg18NCBI36
Celera121,815,754 - 1,896,258 (+)NCBI
Cytogenetic Map12p13.33NCBI
HuRef1228,476 - 140,365 (+)NCBIHuRef
CHM1_112174,887 - 286,602 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IQSEC3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605175
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.