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Gene: IQSEC3 (IQ motif and Sec7 domain ArfGEF 3) Homo sapiens
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Symbol: IQSEC3
Name: IQ motif and Sec7 domain ArfGEF 3
Description: Predicted to have ARF guanyl-nucleotide exchange factor activity. Predicted to be involved in actin cytoskeleton organization. Localizes to the cytosol and nucleoplasm; PARTICIPATES IN endocytosis pathway; INTERACTS WITH aflatoxin B1; benzo[a]pyrene; benzo[e]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IQ motif and Sec7 domain 3; IQ motif and SEC7 domain-containing protein 3; KIAA1110; MGC30156
Orthologs:
Mus musculus (house mouse) : Iqsec3 (IQ motif and Sec7 domain 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Iqsec3 (IQ motif and Sec7 domain ArfGEF 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Iqsec3 (IQ motif and Sec7 domain ArfGEF 3)
Pan paniscus (bonobo/pygmy chimpanzee) : IQSEC3 (IQ motif and Sec7 domain ArfGEF 3)
Canis lupus familiaris (dog) : IQSEC3 (IQ motif and Sec7 domain 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Iqsec3 (IQ motif and Sec7 domain ArfGEF 3)
Sus scrofa (pig) : IQSEC3 (IQ motif and Sec7 domain ArfGEF 3)
more info ...
Related Pseudogenes: IQSEC3P1   IQSEC3P2   IQSEC3P3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381266,767 - 178,455 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712176,049 - 287,626 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,803 - 150,755 (+)NCBINCBI36hg18NCBI36
Celera121,815,754 - 1,896,258 (+)NCBI
Cytogenetic Map12p13.33NCBI
HuRef1228,476 - 140,365 (+)NCBIHuRef
CHM1_112174,887 - 286,602 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IQSEC3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605175
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.