Gene: ERI2 (ERI1 exoribonuclease family member 2) Homo sapiens
Analyze
Symbol:
ERI2
Name:
ERI1 exoribonuclease family member 2
Description:
Predicted to have 3'-5'-exoribonuclease activity and single-stranded DNA 3'-5' exodeoxyribonuclease activity. Predicted to be involved in DNA metabolic process and RNA phosphodiester bond hydrolysis, exonucleolytic; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; amiodarone.
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
enhanced RNAi three prime mRNA exonuclease homolog 2; ERI1 exoribonuclease 2; EXOD1; exonuclease domain containing 1; exonuclease domain-containing protein 1; exoribonuclease 2; KIAA1504; MGC16943; ZGRF5; zinc finger, GRF-type containing 5
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Mus musculus (house mouse):
Eri2 (exoribonuclease 2) HGNC
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):
Eri2 (ERI1 exoribonuclease family member 2) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Chinchilla lanigera (long-tailed chinchilla):
Eri2 (ERI1 exoribonuclease family member 2) NCBI
Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):
ERI2 (ERI1 exoribonuclease family member 2) NCBI
Ortholog
Canis lupus familiaris (dog):
ERI2 (ERI1 exoribonuclease family member 2) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Eri2 (ERI1 exoribonuclease family member 2) NCBI
Ortholog
Sus scrofa (pig):
ERI2 (ERI1 exoribonuclease family member 2) HGNC
EggNOG, Ensembl, NCBI, OrthoDB, Panther
Alliance orthologs 3
Mus musculus (house mouse):
Eri2 (exoribonuclease 2)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Rattus norvegicus (Norway rat):
Eri2 (ERI1 exoribonuclease family member 2)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):
eri2 (ERI1 exoribonuclease family member 2)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, ZFIN)
Drosophila melanogaster (fruit fly):
Snp
Alliance
DIOPT (Ensembl Compara, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup)
Allele / Splice:
See ClinVar data
Latest Assembly:
GRCh38 - Human Genome Assembly GRCh38
Position:
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 16 20,780,193 - 20,806,472 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh37 16 20,791,515 - 20,817,798 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 16 20,699,016 - 20,725,296 (-) NCBI NCBI36 hg18 NCBI36 Celera 16 20,101,413 - 20,127,694 (-) NCBI Cytogenetic Map 16 p12.3 NCBI HuRef 16 19,326,790 - 19,353,149 (-) NCBI HuRef CHM1_1 16 20,878,433 - 20,904,709 (-) NCBI CHM1_1
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Gene-Chemical Interaction Annotations
1-naphthyl isothiocyanate decreases expression ISO RGD:1583889 6480464 1-Naphthylisothiocyanate results in decreased expression of ERI2 mRNA CTD PMID:30723492 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:1332128 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:1332128 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1332128 6480464 Tetrachlorodibenzodioxin affects the expression of ERI2 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ERI2 mRNA CTD PMID:22574217 4,4'-diaminodiphenylmethane affects expression ISO RGD:1332128 6480464 4, 4'-diaminodiphenylmethane affects the expression of ERI2 mRNA CTD PMID:18648102 aflatoxin B1 increases expression ISO RGD:1332128 6480464 Aflatoxin B1 results in increased expression of ERI2 mRNA CTD PMID:19770486 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of ERI2 mRNA CTD PMID:22100608 amiodarone increases expression EXP 6480464 Amiodarone results in increased expression of ERI2 mRNA CTD PMID:19774075 arsane affects methylation EXP 6480464 Arsenic affects the methylation of ERI2 gene CTD PMID:25304211 arsenic atom affects methylation EXP 6480464 Arsenic affects the methylation of ERI2 gene CTD PMID:25304211 benzo[a]pyrene increases expression ISO RGD:1332128 6480464 Benzo(a)pyrene results in increased expression of ERI2 mRNA CTD PMID:19770486 butanal decreases expression EXP 6480464 butyraldehyde results in decreased expression of ERI2 mRNA CTD PMID:26079696 carbon nanotube increases expression ISO RGD:1332128 6480464 Nanotubes, Carbon results in increased expression of ERI2 mRNA CTD PMID:25554681 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of ERI2 mRNA CTD PMID:27392435 copper(II) sulfate decreases expression EXP 6480464 Copper Sulfate results in decreased expression of ERI2 mRNA CTD PMID:19549813 coumestrol multiple interactions EXP 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ERI2 mRNA CTD PMID:19167446 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of ERI2 mRNA CTD PMID:25562108 dicrotophos decreases expression EXP 6480464 dicrotophos results in decreased expression of ERI2 mRNA CTD PMID:28302478 Enterolactone multiple interactions EXP 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ERI2 mRNA CTD PMID:19167446 ethyl methanesulfonate increases expression EXP 6480464 Ethyl Methanesulfonate results in increased expression of ERI2 mRNA CTD PMID:23649840 formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of ERI2 mRNA CTD PMID:23649840 lead diacetate increases expression ISO RGD:1583889 6480464 lead acetate results in increased expression of ERI2 mRNA CTD PMID:22641619 lead(0) affects expression EXP 6480464 Lead affects the expression of ERI2 mRNA CTD PMID:28903495 lead(2+) affects expression EXP 6480464 Lead affects the expression of ERI2 mRNA CTD PMID:28903495 methyl methanesulfonate increases expression EXP 6480464 Methyl Methanesulfonate results in increased expression of ERI2 mRNA CTD PMID:23649840 orphenadrine affects expression ISO RGD:1583889 6480464 Orphenadrine affects the expression of ERI2 mRNA CTD PMID:23665939 oxaliplatin decreases expression ISO RGD:1583889 6480464 oxaliplatin results in decreased expression of ERI2 mRNA CTD PMID:25729387 oxaliplatin multiple interactions ISO RGD:1583889 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of ERI2 mRNA CTD PMID:25729387 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of ERI2 mRNA CTD PMID:21420995 , PMID:29067470 pentanal decreases expression EXP 6480464 pentanal results in decreased expression of ERI2 mRNA CTD PMID:26079696 phenobarbital affects expression ISO RGD:1332128 6480464 Phenobarbital affects the expression of ERI2 mRNA CTD PMID:23091169 quercitrin increases expression EXP 6480464 quercitrin results in increased expression of ERI2 mRNA CTD PMID:25193878 silicon dioxide decreases expression EXP 6480464 Silicon Dioxide analog results in decreased expression of ERI2 mRNA CTD PMID:25895662 silicon dioxide decreases expression ISO RGD:1332128 6480464 Silicon Dioxide results in decreased expression of ERI2 mRNA CTD PMID:19073995 sodium dichromate decreases expression ISO RGD:1583889 6480464 sodium bichromate results in decreased expression of ERI2 mRNA CTD PMID:25993096 tetrachloroethene decreases expression ISO RGD:1332128 6480464 Tetrachloroethylene results in decreased expression of ERI2 mRNA CTD PMID:28973375 topotecan decreases expression ISO RGD:1583889 6480464 Topotecan results in decreased expression of ERI2 mRNA CTD PMID:25729387 topotecan multiple interactions ISO RGD:1583889 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of ERI2 mRNA CTD PMID:25729387 urethane decreases expression EXP 6480464 Urethane results in decreased expression of ERI2 mRNA CTD PMID:28818685 valproic acid decreases expression ISO RGD:1332128 6480464 Valproic Acid analog results in decreased expression of ERI2 mRNA, Valproic Acid results in decreased expression of ERI2 mRNA CTD PMID:21427059 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of ERI2 mRNA CTD PMID:25979313 vinclozolin increases expression ISO RGD:1583889 6480464 vinclozolin results in increased expression of ERI2 mRNA CTD PMID:23034163
Gene Ontology Annotations
Gene Ontology Annotations
