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Gene: PLEKHG6 (pleckstrin homology and RhoGEF domain containing G6) Homo sapiens
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Symbol: PLEKHG6
Name: pleckstrin homology and RhoGEF domain containing G6
Description: Predicted to have GTPase activator activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in positive regulation of GTPase activity. Localizes to the cell junction and centrosome; INTERACTS WITH 17beta-estradiol; aflatoxin B1; aflatoxin B2.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ10665; MGC126315; MGC126353; MGC126354; MyoGEF; myosin II interacting GEF; myosin interacting guanine nucleotide exchange factor; myosin-interacting guanine nucleotide exchange factor; PH domain-containing family G member 6; pleckstrin homology domain containing, family G (with RhoGef domain) member 6; pleckstrin homology domain-containing family G member 6
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,310,436 - 6,328,506 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37126,419,602 - 6,437,672 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,289,863 - 6,307,932 (+)NCBINCBI36hg18NCBI36
Celera128,036,249 - 8,054,316 (+)NCBI
Cytogenetic Map12p13.31NCBI
HuRef126,272,681 - 6,290,919 (+)NCBIHuRef
CHM1_1126,418,827 - 6,436,893 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PLEKHG6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605382
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.