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Gene: TPM3 (tropomyosin 3) Homo sapiens
Symbol: TPM3
Name: tropomyosin 3
Description: Predicted to have actin filament binding activity. Predicted to be involved in actin filament organization. Localizes to the cytosol and stress fiber. Implicated in nemaline myopathy 1. Biomarker of thyroid gland papillary carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha-tropomyosin, slow skeletal; CAPM1; CFTD; cytoskeletal tropomyosin TM30; epididymis luminal protein 189; epididymis secretory sperm binding protein Li 82p; FLJ41118; gamma-tropomyosin; heat-stable cytoskeletal protein 30 kDa; HEL-189; HEL-S-82p; hscp30; hTM5; MGC14582; MGC3261; MGC72094; NEM1; nemaline myopathy 1, autosomal dominant; OK/SW-cl.5; TM-5; TM3; TM30; TM30nm; TM5; TPM3nu; TPMsk3; TRK; tropomyosin 3 nu; tropomyosin alpha-3 chain; tropomyosin gamma; tropomyosin-3; tropomyosin-5
Mus musculus (house mouse) : Tpm3 (tropomyosin 3, gamma)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tpm3 (tropomyosin 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tpm3 (tropomyosin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TPM3 (tropomyosin 3)
Canis lupus familiaris (dog) : TPM3 (tropomyosin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tpm3 (tropomyosin 3)
Sus scrofa (pig) : TPM3 (tropomyosin 3)
more info ...
Related Pseudogenes: TPM3P1   TPM3P2   TPM3P3   TPM3P4   TPM3P5   TPM3P6   TPM3P7   TPM3P8   TPM3P9  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381154,155,304 - 154,192,100 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371154,127,780 - 154,164,611 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361152,394,404 - 152,431,233 (-)NCBINCBI36hg18NCBI36
Celera1127,199,522 - 127,236,328 (-)NCBI
Cytogenetic Map1q21.3NCBI
HuRef1125,491,124 - 125,527,939 (-)NCBIHuRef
CHM1_11155,524,124 - 155,560,933 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TPM3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605427
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.