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Gene: BMX (BMX non-receptor tyrosine kinase) Homo sapiens
Symbol: BMX
Name: BMX non-receptor tyrosine kinase
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bone marrow tyrosine kinase gene in chromosome X protein; BTK-like on X chromosome; cytoplasmic tyrosine-protein kinase BMX; epithelial and endothelial tyrosine kinase; ETK; Etk/Bmx cytosolic tyrosine kinase; NTK38 tyrosine kinase; PSCTK2; PSCTK3
Mus musculus (house mouse) : Bmx (BMX non-receptor tyrosine kinase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bmx (BMX non-receptor tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bmx (BMX non-receptor tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : BMX (BMX non-receptor tyrosine kinase)
Canis lupus familiaris (dog) : BMX (BMX non-receptor tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bmx (BMX non-receptor tyrosine kinase)
Sus scrofa (pig) : BMX (BMX non-receptor tyrosine kinase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X15,500,777 - 15,556,529 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X15,482,356 - 15,574,652 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X15,428,821 - 15,484,573 (+)NCBINCBI36hg18NCBI36
CeleraX19,634,383 - 19,690,144 (+)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX13,280,437 - 13,329,298 (+)NCBIHuRef
CHM1_1X15,549,836 - 15,605,599 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on BMX
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605440
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.