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Gene: SUB1 (SUB1 regulator of transcription) Homo sapiens
Symbol: SUB1
Name: SUB1 regulator of transcription
Description: Exhibits identical protein binding activity; single-stranded DNA binding activity; and transcription coactivator activity. Involved in negative regulation of DNA metabolic process and regulation of transcription by RNA polymerase II. Localizes to nucleolus; nucleoplasm; and transcription regulator complex; PARTICIPATES IN RNA polymerase III transcription pathway; INTERACTS WITH (-)-demecolcine; 2,3,7,8-tetrachlorodibenzodioxine; 2-methylcholine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: activated RNA polymerase II transcription cofactor 4; activated RNA polymerase II transcriptional coactivator p15; MGC102747; p14; P15; PC4; positive cofactor 4; SUB1 homolog; SUB1 homolog, transcriptional regulator
Mus musculus (house mouse) : Sub1 (SUB1 homolog, transcriptional regulator)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sub1 (SUB1 regulator of transcription)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sub1 (SUB1 regulator of transcription)
Pan paniscus (bonobo/pygmy chimpanzee) : SUB1 (SUB1 regulator of transcription)
Canis lupus familiaris (dog) : SUB1 (SUB1 regulator of transcription)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sub1 (SUB1 regulator of transcription)
Sus scrofa (pig) : SUB1 (SUB1 regulator of transcription)
Chlorocebus sabaeus (African green monkey) : SUB1 (SUB1 regulator of transcription)
Heterocephalus glaber (naked mole-rat) : Sub1 (SUB1 regulator of transcription)
more info ...
Related Pseudogenes: SUB1P1   SUB1P2   SUB1P3   SUB1P4  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl532,531,633 - 32,604,079 (+)EnsemblGRCh38hg38GRCh38
GRCh38532,531,778 - 32,604,079 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37532,585,605 - 32,604,185 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36532,621,434 - 32,637,820 (+)NCBINCBI36hg18NCBI36
Celera532,467,253 - 32,485,840 (+)NCBI
Cytogenetic Map5p13.3NCBI
HuRef532,553,427 - 32,572,031 (+)NCBIHuRef
CHM1_1532,587,724 - 32,606,294 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SUB1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1605698
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-06-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.